5-HT4 Receptors in the Brain and Periphery

5-HT4 Receptors in the Brain and Periphery

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This book provides a comprehensive, up-to-date review of the distribution, pharmacology and physiology of central 5-hydroxytryptamine (5-HT)4 receptors. The 5-HT receptor subtypes exhibit a unique pharmacology, distribution and function, of which the 5-HT4 receptor has been one of the most intensively studied in recent years, both from a basic research standpoint and as a target for novel therapeutics.

1. Medicinal Chemistry of 5-HT4 Receptor Ligands
2. Molecular Biology of 5-HT4 Receptors
3. Localization of 5-HT4 Receptors in Vertebrate Brain and Their Potential Behavioral Roles
4. Central 5-HT4 Receptors: Electrophysiology
5. Neurochemical Consequences Following Pharmacological Manipulation of Central 5-HT4 Receptors
6. 5-Hydroxytryptamine and Human Heart Function: The Role of 5-HT4 Receptors
7. 5-HT4 Receptors in Gastrointestinal Tract
8. 5-HT4 Receptors in Lower Urinary Tract Tissues
9. The 5-HT4 Receptor in the Adrenal Gland
10. Therapeutic Applications of 5-HT4 Receptor Agonists and Antagonists.
ISBN 978-3-662-05555-7
Article number 9783662055557
Media type Book
Edition number Softcover reprint of the original 1st ed. 1998
Copyright year 2013
Publisher Springer, Berlin
Length XIII, 229 pages
Illustrations XIII, 229 p. 19 illus.
Language English