Bioorganic and Enzymatic Catalysis
Bioorganic and Enzymatic Catalysis
Preface vii
1 Enzymatic C C Bond Formation by Aldol Reactions 1
Aldolases 1
Class I Aldolases 1
Bioorganic Class I Aldolase Reactions 3
Class II Aldolases 9
Class II Aldolase Mimics 11
References 13
2 Fatty Acid- and Polyketide-Synthases - Claisen-Type C C Bond Formation 15
Biomimetic Decarboxylative C C Bond Formation 20
References 23
3 Carbenium-Ion-Driven C C Bond Formations - Terpenes 25
Enzyme-like Cyclisations Involving Carbenium Ions 30
References 41
4 Oxidations Catalysed by Heme Complexes 43
Monooxygenases 43
Cytochromes P 450 45
Synthetic P450 Enzyme Models 51
Chloroperoxidase (CPO) 57
Synthetic Enzyme Mimics of Chloroperoxidase (CPO) 60
NO Synthase (NOS) 63
References 67
5 Oxidations Catalysed by Non-heme Complexes and Other Co-factors 69
Methane Monooxygenase 69
Active Site Analogues of Methane Monooxygenase 71
Enzyme Mimics of Cu Monooxygenases 75
Flavin-dependent Monooxygenases 78
Enzyme Mimics of Baeyer-Villiger Monooxygenases 83
References 95
6 C-H Activation 97
References 110
7 Dioxygenases 111
Metal Complexes Displaying Dioxygenase-like Reactivity 127
References 134
8 Oxidoreductases 137
Cytochrome c Oxidase 148
References 150
9 Synthetic Systems That Mimic Certain Aspects of Oxidoreductases 153
References 173
Index 175
Login
Woggon, Wolf-D.
| ISBN | 9783527336838 |
|---|---|
| Media type | Book |
| Copyright year | 2023 |
| Publisher | Wiley-VCH |
| Language | English |
