Engineering and Application of Pluripotent Stem Cells

Engineering and Application of Pluripotent Stem Cells

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This book reviews the latest biotechnological advances with pluripotent stem cells, exploring their application in tissue engineering and medicinal chemistry. Chapters from expert contributors cover topics such as the production of transgene-free induced pluripotent stem cells (iPSCs), expansion, controlled differentiation and programming of pluripotent stem cells, and their genetic instability. Particular attention is given to the application of the pluripotent stem cells for vascularision of engineered tissue and for drug screening.

This book will appeal to researchers working in regenerative medicine and drug discovery, and to bioengineers and professionals interested in stem cell research.



Nonintegrating Human Somatic Cell Reprogramming Methods
Scalable Expansion of Pluripotent Stem Cells
Scalable Cardiac Differentiation of Pluripotent Stem Cells Using Specific Growth Factors and Small Molecules
 Specific Cell (Re-)Programming: Approaches and Perspectives
Bioengineered Cardiac Tissue Based 4 on Human Stem Cells for Clinical Application
Human Pluripotent Stem Cells to Engineer Blood Vessels
Targeted Gene Editing in Human Pluripotent Stem Cells Using Site-Specific Nucleases
Acquired Genetic and Epigenetic Variation in Human Pluripotent Stem Cells
Requirements for Using iPSC-Based Cell Models for Assay Development in Drug Discovery.
ISBN 978-3-030-08817-0
Article number 9783030088170
Media type Book
Copyright year 2019
Publisher Springer, Berlin
Length VII, 228 pages
Illustrations VII, 228 p.
Language English