Experimental Design and Reproducibility in Preclinical Animal Studies
Experimental Design and Reproducibility in Preclinical Animal Studies
This highly-readable text provides grounds on how to plan and conduct animal experiments that can be reproduced by others. The book touches on factors that may impact the reproducibility of animal studies including: the animal genetic background, the animal microbial flora, environmental and physiological variables affecting the animal, animal welfare, statistics and experimental design, systematic reviews of animal studies, and the publishing process.
The book addresses advanced undergraduates, graduate students and all scientists working with animals.
An introduction to reproducibility in the context of animal research
Rodent Genetics
Animal and environmental factors that influence reproducibility
Microbiology and Microbiome
Effects of untreated pain, anesthesia and analgesia in animal experimentation
Why do we need a statistical experiment design
Statistical tests and Sample size calculations
Design of experiments
Scholarly Publishing and Scientific Reproducibility
Systematic reviews
Planning animal experiments.
Sánchez Morgado, José M.
Brønstad, Aurora
| ISBN | 978-3-030-66149-6 |
|---|---|
| Media type | Book |
| Copyright year | 2022 |
| Publisher | Springer, Berlin |
| Length | VI, 277 pages |
| Illustrations | VI, 277 p. 52 illus., 39 illus. in color. |
| Language | English |
