Fragment-Based Drug Discovery and X-ray Crystallography

Fragment-Based Drug Discovery and X-ray Crystallography

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Introduction to Fragment-Based Drug Discovery, by Daniel A. Erlanson

Fragment Screening Using X-Ray Crystallography, by Thomas G. Davies and Ian J. Tickle

Hsp90 Inhibitors and Drugs from Fragment and Virtual Screening, by Stephen Roughley, Lisa Wright, Paul Brough, Andrew Massey and Roderick E. Hubbard

Combining NMR and X-ray Crystallography in Fragment-Based Drug Discovery: Discovery of Highly Potent and Selective BACE-1 Inhibitors, by Daniel F. Wyss, Yu-Sen Wang, Hugh L. Eaton, Corey Strickland, Johannes H. Voigt, Zhaoning Zhu and Andrew W. Stamford

Combining Biophysical Screening and X-Ray Crystallography for Fragment-Based Drug Discovery, by Michael Hennig, Armin Ruf and Walter Huber

Targeting Protein-Protein Interactions and Fragment-Based Drug Discovery, by Eugene Valkov, Tim Sharpe, May Marsh, Sandra Greive and Marko Hyvönen

Fragment Screening and HIV Therapeutics, by Joseph D. Bauman, Disha Patel and Eddy Arnold

Fragment-Based Approaches and Computer-Aided Drug Discovery, by Didier Rognan



D. A. Erlanson
Introduction to Fragment-Based Drug Discovery

T. G. Davies
Ian J. Tickle
Fragment Screening Using X-Ray Crystallography

S. Roughley
L. Wright
P. Brough
A. Massey
R. E. Hubbard
Hsp90 Inhibitors and Drugs from Fragment and Virtual Screening

D. F. Wyss
Y.-S. Wang
H. L. Eaton
C. Strickland
J.s H. Voigt
Z. Zhu
A. W. Stamford
Combining NMR and X-ray Crystallography in Fragment-Based Drug Discovery: Discovery of Highly Potent and Selective BACE-1 Inhibitors

M. Hennig
A. Ruf
Walter HuberCombining Biophysical Screening and X-Ray Crystallography for Fragment-Based Drug Discovery

E. Valkov
T. Sharpe
M. Marsh
Sa. Greive
M. Hyvönen
Targeting Protein-Protein Interactions and Fragment-Based Drug Discovery

J.h D. Bauman
D. Patel
E. Arnold
Fragment Screening and HIV Therapeutics

D. Rognan
Fragment-Based Approaches and Computer-Aided Drug Discovery.


ISBN 978-3-642-27539-5
Media type Book
Copyright year 2012
Publisher Springer, Berlin
Length XII, 228 pages
Language English