Late-Stage Functionalization and Diversification in Organic Synthesis

Methods and Applications

Late-Stage Functionalization and Diversification in Organic Synthesis

Methods and Applications

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Provides a much-needed overview of the most important methods for the late-stage transformation of complex molecules, such as C-H functionalization, C-X bond activation, cross-coupling reactions, fluorination, etc.

Foreword
Preface
PART I: LATE-STAGE FUNCTIONALIZATION STRATEGIES
1. Late-Stage Functionalization by Transition Metal Catalyzed C-H Functionalization
2. Light-Triggered Methods for Late-Stage Functionalization
3. Electrochemical Late-Stage Functionalization
4. Flow Chemistry Applied for Late-Stage Functionalization and other Functional Group-Tolerant Manipulation
5. Radioisotope Insertion through Late-Stage Functionalization
PART II: DIVERSITY-ORIENTED SYNTHESIS
6. Late-Stage Functionalization Strategies Using C-O Bond Activation
7. C-N Bond Activation under Redox-Neutral Conditions
8. Late-Stage Functionalization by C-S Bond Activation
PART III: MOLECULAR/STEREOCHEMICAL EDITING
9. Molecular Editing as an Efficient Tool to Access Functionalized Organic Molecules
ISBN 9783527354184
Media type Book
Edition number 1. Auflage
Copyright year 2026
Publisher Wiley-VCH GmbH Wiley-VCH GmbH, Boschstrasse 12, DE-69469 Weinheim
Length 304 pages
Language English