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Batch Processes: Monitoring and Process Understanding offers a comprehensive examination of batch process modeling, monitoring, and control, emphasizing PAT and LSB methods such as principal component analysis (PCA) and partial least squares (PLS). Batch Processes: Monitoring and Process Understanding addresses practical challenges in batch data analysis, such as preprocessing, missing data imputation, equalization, synchronization (DTW, RGTW, Multisynchro), and multi-phase modeling. Real-world case studies and hands-on MATLAB examples using the MVBatch toolbox bridge theory and practice, demonstrating how LSB methods improve quality, safety, and economic and ecological outcomes across chemical, biotech, and pharmaceutical industries. Batch Processes: Monitoring and Process Understanding is an essential guide for professionals in chemical, biotech and pharmaceutical industries seeking both foundational knowledge and advanced techniques in batch processes and data analysis.

Prologue: Challenges for the third millennium
1 Introduction
1.1 Industrial batch processes
1.2 Types of sensors
1.3 Batch process modeling
1.4 Bilinear modeling cycle for batch process monitoring
2 Data-driven models based on latent variables
2.1 Compression
2.2 Principal components analysis
2.3 Regression
2.4 Regression models based on latent variables
2.5 Multivariate Exploratory Data Analysis
2.6 Missing data
3 Batch data equalization
3.1 Introduction
3.2 Challenges in batch equalization
3.3 Equalization of variables within a batch
3.4 Multi-rate system
4 Batch synchronization
4.1 Introduction
4.2 Synchronization approaches
4.3 Effect of synchronization on the correlation structure
5 Batch data preprocessing
5.1 Batch preprocessing operations
5.2 Mean centering
5.3 Scaling
6 Three-way to two-way transformation
6.1 Introduction
6.2 Single-model approach
6.3 K-models approach
6.4 Multi-phase Approach
6.5 Conclusions
7 Batch Process Data Analysis and Statistical Monitoring
7.1 Introduction
7.2 Historical Batch Data Analysis
7.3 Batch Multivariate Statistical Process Control (BMSPC)
7.4 Practical issues
ISBN 9783527326402
Article number 9783527326402
Media type Book
Edition number 1. Auflage
Copyright year 2026
Publisher Wiley-VCH GmbH Wiley-VCH GmbH, Boschstrasse 12, DE-69469 Weinheim
Length 256 pages
Illustrations 300 SW-Abb., 7 Farbabb.
Language English