Color Atlas of Histopathology of the Cervix Uteri

Color Atlas of Histopathology of the Cervix Uteri

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This edition of this atlas provides a detailed histopathological diagnosis of cervical disease emphasizing carcinogenesis, and correlating morphologic changes with clinical aspects. Instructions of how to obtain and handle tissue samples are followed by a description of the normal histology, of the action of steroid hormones on the cervix, and of the various forms of regeneration and inflammation. The section on etiology and pathogenesis of HPV-induced neoplasia has been enlarged to explain new insights into cellular and nuclear deregulation at the molecular level. A chapter on immunohistochemistry has been added which includes refined detection methods, e.g., with p16 for the early differential diagnosis of premalignant lesions. The latest advances in molecular biological research, with predictive subdivision of neoplasias, facilitate the choice of the proper therapy. All chapters - supported by over 20 new microphotographs - have been revised to include advances in the interpretation and management of cervical disease. The tumor nomenclature is adapted to the new WHO classification; the ICD-O code has been added. The reference list is updated with relevant publications.

1;Preface to the Second Edition;5 2;Preface to the First Edition;6 3;Contents;8 4;Screening for Cervical Cancer Precursors to Prevent Invasive Disease;12 5;Methods of Obtaining and Preparing Cervical Tissue for Histological Examination;13 6;Immunohistochemistry and In Situ Hybridization;18 7;Normal Histology, Regeneration, and Repair;24 8;Vestigial and Heterotopic Tissues;43 9;Hormonally Induced Changes;53 10;Inflammatory Lesions;68 11;Benign Tumors;85 12;Premalignant Lesions;93 13;Malignant Tumors;128 14;References;191 15;Subject Index;204
ISBN 9783540297260
Article number 9783540297260
Media type eBook - PDF
Edition number 2. Aufl.
Copyright year 2005
Publisher Springer-Verlag
Length 196 pages
Language English
Copy protection Digital watermarking