Fast Facts: Comprehensive Genomic Profiling
Making precision medicine possible
eBook
Cancer is a multifaceted disease in which genetic changes induce uncontrolled tumor growth. Genomic characterization of cancer is now leading to better diagnostic, prognostic and predictive biomarkers, and effective individualized management. 'Fast Facts: Comprehensive Genomic Profiling' provides a crash course in the science, methods and application of genomic profiling. Assuming only the most basic knowledge - or memory - of cell biology, the authors provide an overview of DNA and RNA biology and next-generation sequencing. This sets in context the descriptions of prognostic and predictive biomarkers for different cancer types and genomic-based treatments. Finally, but importantly, some of the practicalities of gaining and interpreting genomic information are described. Whether you need a primer or a refresher, this short colorful book demystifies this complex subject. Contents: Genetic mutations and biomarkers Understanding next-generation sequencing Elements of comprehensive genomic profiles Role in precision oncology Predictive and prognostic biomarkers Overcoming barriers to genotype-directed therapy
Rapoport, Bernardo L.
Troncone, Giancarlo
Schmitt, Fernando
Nayler, Simon
| ISBN | 9783318068191 |
|---|---|
| Article number | 9783318068191 |
| Media type | eBook - ePUB |
| Copyright year | 2020 |
| Publisher | Karger |
| Length | 108 pages |
| Language | English |
| Copy protection | Adobe DRM |
