From Nucleic Acids Sequences to Molecular Medicine

From Nucleic Acids Sequences to Molecular Medicine

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Despite a half century of structural, biophysical and biochemical investigations of ribonucleic acids, they are still mysterious. RNAs stand at fertile crossroads of disciplines, integrating concepts from genomics, proteomics, dynamics as well as biochemistry and molecular biology. From 20 years it is clear, that genetic regulation of eukaryotic organisms has been misunderstood for the last years that the expression of genetic information is effected only by proteins. Basic understanding of nucleic acids has enhanced our foundation to probe novel biological functions. This is especially evident for RNA molecules whose functionality, maturation, and regulation require formation of correct secondary structure through encoded base-pairing interactions.
ISBN 9783642274268
Article number 9783642274268
Media type eBook - PDF
Edition number 2. Aufl.
Copyright year 2012
Publisher Springer-Verlag
Length 654 pages
Illustrations w. 120 ill., 46 col. ill.
Language English
Copy protection Digital watermarking