Heart Rate and Rhythm
Pathological heart rhythms are a major health issue. In this book experts from various fields provide an important context for understanding the complicated molecular and cellular mechanisms that underlie normal and pathophysiological cardiac rhythms.
Individual chapters cover a full range of topics, including the ionic basis of pacemaking, the role of specific channels and transporters in sinoatrial node pacemaking, altered intracellular Ca2+ handling in response to disease, computer modeling of the action potentials of pacemaker and working cardiomyocytes, genetic and molecular basis of inherited arrhythmias and a review of established and novel antiarrhythmic agents. Due to the key importance of the specialized pacemaker cells and tissue (sinoatrial and atrioventricular nodes) in maintaining heart rate and rhythm, special emphasis is placed on the peculiar electrophysiology of these cells.
Normal Cardiac Rhythm and Pacemaker Activity
Modeling of Rhythm in the HeartCardiac Development and Anatomy
Mechanisms of Acquired Arrhythmia
Mechanisms of Inherited Arrhythmia
Role of Specific Channels and Transporters in Arrhythmia
Drugs and Cardiac Arrhythmia.
Tripathi, Onkar N.
Ravens, Ursula
Sanguinetti, Michael C.
| ISBN | 978-3-642-17574-9 |
|---|---|
| Media type | Book |
| Copyright year | 2011 |
| Publisher | Springer, Berlin |
| Length | XXII, 678 pages |
| Language | English |
