Induction chemotherapy, as part of an integrated plan of management for locally advanced cancers, is being practiced throughout the world, but frequently teams are unaware of the work being undertaken in other institutions. This book aims to present the full range of management techniques used in induction chemotherapy within one accessible volume. It provides up-to-date information on pioneering and cutting edge practices and documents the advantages of integrated treatment schedules. Patient selection is discussed, and each of the cancer types for which induction therapy has proved important is considered in detail. All who are responsible for the treatment of patients with locally advanced cancers will find this book to be an invaluable source of information. It will be particularly interesting for specialist oncologists aiming to set up fully comprehensive cancer centers and for health administrators wishing to learn about the benefits of establishing such centers in strategic locations.

Introduction: Overview, History, Terminology and Early Clinical Experience.-The Principle of Dose-Response in Antineoplastic Drug Delivery

Drug Removal Systems and Induction Chemotherapy
Cryotherapy
Local and Regional Hyperthermia
The Role of Hypoxia and Hyperthermia in Chemotherapy
Induction Chemotherapy in Head and Neck Cancers
Isolated Thoracic Perfusion with Carotid Artery Infusion for Advanced and Chemoresistant Tumors of the Parotid Gland
Induction Systemic Chemotherapy for Breast Cancer
Induction Intra-arterial Chemotherapy (IAC) with Epirubicin and Mitoxantrone in Locally Advanced Breast Cancer.-Induction Bidirectional Chemotherapy for Gastric Cancer with Peritoneal Dissemination
Gastric Cancer
Oesophageal Cancer
Regional Chemotherapy for Recurrent Platin Refractory Ovarian Cancer
Penile Cancer Treated by Intra-aortic Infusion Chemotherapy
Isolated Limb Perfusion for Melanoma
Interventional Radiological Procedures for Port-Catheter Implantation
Induction Chemotherapy for Hepatocellular Carcinoma
Systemic Induction Chemotherapy for Advanced Stage Epithelial Ovarian Cancer
Induction Chemotherapy for Cervical Cancer
Induction Treatment in Sarcomas
Induction Chemotherapy in Treatment of Sarcomas
Liver Metastases.-Isolated Thoracic Perfusion with Chemofiltration (ITP-F) for Advanced and Pre-treated Non-Small-Cell Lung Cancer.-Isolation Perfusion Systems: Lungs
Metastatic Cancers in Lung: Isolated Lung Perfusion Clinical Studies
Systemic and Regional Chemotherapy for Advanced and Metastasized Pancreatic Cancer
Conclusion.