This book gathers the proceedings of the 17^th International Conference on Intracranial Pressure and Neuromonitoring, held in Leuven, Belgium in September 2019. It provides an overview of the current understanding, underlying research and future perspectives concerning pathophysiology, biophysics, monitoring and management in traumatic and non-traumatic acute brain injury, hydrocephalus and spinal cord injury, including cerebrovascular autoregulation impairment in neurological as well as non-neurological diseases. The peer-reviewed contributions were prepared by specialists in neurosurgery, neurointensive care and neuroanesthesiology, as well as prominent experts from the fields of physiology, clinical and biomedical engineering, mathematics and informatics. The book continues the time-honored tradition of publishing key presentations from the ICP Conferences in order to facilitate their dissemination within the clinical and research community.

PART I ~ NEUROMONITORING AND MANAGEMENT IN ADULT TRAUMATIC BRAIN INJURY 1 ~ 1129 Microcirculatory Biomarkers of Secondary Cerebral Ischemia at Traumatic Brain Injury.- 2 ~ 1165 Visualisation of ICP Insults After Severe TBI; Influence of Individualised Limits of Reactivity.- 3 ~ 1178 Pressure Challenge Impact on Cerebral Critical Closing Pressure and Effective CPP in Traumatic Brain Injury Patients.- 4 ~ 1204 Semi-automated CT Volumetry as Proxy for Intracranial Pressure in Patients with Severe Traumatic Brain Injury: Clinical Feasibility Study.- 5 ~ 1224 The Error and Consequences of Inaccurate Estimation of Mean Blood Flow Velocity in Cerebral Arteries.- 6 ~ 1235 Analysis of Association Between Lung Function and Brain Tissue Oxygen Tension in Severe Traumatic Brain Injury.- 7 ~ 1246 A Comparison of Two ICP Calculation Methods and Their Effects on Mean-ICP and ICP Dose.- 8 ~ 1263 External Hydrocephalus After Traumatic Brain Injury: Retrospective Study of 102 Patients.- 9 ~ 1288 Analyzing Cardio-Cerebral Crosstalks in an Adult Cohort from CENTER-TBI.- 10 ~ 1308 Cerebrovascular Consequences of Elevated Intracranial Pressure After Traumatic Brain Injury.- PART II ~ NEUROMONITORING AND MANAGEMENT IN ADULT NON-TRAUMATIC BRAIN INJURY 11 ~ 1130 The Assessment of Cerebral Autoregulation in the Perifocal Zone of a Chronic Subdural Hematoma.- 12 ~ 1210 Noninvasive Intracranial Pressure Monitoring in Chronic Stroke Patients with Sedentary Behavior - Pilot Study.- 13 ~ 1291 Investigating Changes in Intracranial Pressure Waveform Morphology in Patients with Ventriculitis Using Clustering.- 14 ~ 1292 Perioperative Dynamics of Intracranial B-waves of Blood Flow Velocity in Basal Cerebral Arteries in Patients with Brain Arteriovenous Malformation.- PART III ~ NEUROMONITORING AND MANAGEMENT IN ADULT MIXED BRAIN INJURY POPULATIONS 15 ~ 1139 The Effect of Hyperthermia on the Intracranial Pressure and Cerebral Autoregulation in Patients with Acute Brain Injury.- 16 ~ 1194 A Comparative Study on the Effect of Early Versus Late Cranioplasty in Cognitive Function.- 17 ~ 1195 Effect of Cranioplasty After Decompressive Craniectomy in Traumatic Versus Non Traumatic Brain Injury on Neurological Function and Cerebral Hemodynamics.- 18 ~ 1221 Brain Multimodal Monitoring in Severe Acute Brain Injury: Is It Relevant for Outcome and Mortality?.- 19 ~ 1239 Long-term Outcome After Decompressive Craniectomy in a Developing Country.- 20 ~ 1357 Predictors of Successful Extubation in Neurocritical Patients.- PART IV ~ NEUROMONITORING AND MANAGEMENT IN THE PEDIATRIC POPULATION 21 ~ 1160 Impaired Autoregulation Following Resuscitation Correlates to Outcome in Pediatric Patients: A Pilot Study.- 22 ~ 1171 Brain Biomarkers in Children After Mild and Severe Brain Traumatic Injury.- 23 ~ 1200 Decompressive Craniectomy for Traumatic Intracranial Hypertension in Children.- 24 ~ 1214 The Use of Direct ICP and Brain Tissue Oxygen Monitoring in the Perioperative Management of Patients with Moyamoya Disease.- PART V ~ NEUROMONITORING TECHNOLOGY 25 ~ 1118 Optic Nerve Sheath Diameter Threshold for Increased Intracranial Pressure Are Not Related to Sex and Age in Traumatic Brain Injury.- 26 ~ 1120 A Noninvasive Method for Monitoring Intracranial Pressure During Postural Changes.- 27 ~ 1187 Arterial and Venous Cerebrovascular Flow Velocities Coupling in Healthy Volunteers and Traumatic Brain Injured Patients.- 28 ~ 1309 Comparison of Waveforms Between Non-invasive and Invasive ICP Monitoring.- PART VI ~ CEREBROVASCULAR AUTOREGULATION IN ACUTE BRAIN INJURY AND CARDIAC SURGERY 29 ~ 1169 An Update on the COGiTATE Phase II Study: Feasibility and Safety of Targeting an Optimal Cerebral Perfusion Pressure as a Patient-Tailored Therapy in Severe Traumatic Brain Injury.- 30 ~ 1223 Quick Assessment of the Low Limi