Overcoming Synthetic Challenges in Medicinal Chemistry

Mechanistic Insights and Solutions

Overcoming Synthetic Challenges in Medicinal Chemistry

Mechanistic Insights and Solutions

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Collection of 150 synthetic problems in medicinal chemistry offering mechanistic insights into complex reactions and potential pitfalls in drug synthesis

Overcoming Synthetic Challenges in Medicinal Chemistry is a comprehensive collection of around 150 challenging organic reactions in medicinal chemistry, drawn from the author's work experience and recent journal and patent publications. Problems are arranged by the structure of the reaction product to make it easier for the reader to find the information needed.

In this book, readers will find information on:

  • General terms and concepts in synthetic organic chemistry and medicinal chemistry
  • Specific reactions leading to desired products or unexpected side products
  • Step-by-step mechanisms, experimental procedures, literature information, and applications for each reaction
  • Ways to reduce mistakes in synthetic work and optimize product synthesis

Overcoming Synthetic Challenges in Medicinal Chemistry serves as a valuable guide for organic chemists, professionals, and job candidates in the pharmaceutical industry, as well as graduates and lecturers at university, helping them grasp complex reactions and gain insight into potential pitfalls and side reactions in drug synthesis.

Tongshuang Li has extensive experience in synthetic organic chemistry and medicinal chemistry, with over 22 years in the pharmaceutical industry and 12 years in academia. Currently, he is working as a chemistry consultant for both biotech companies and academics. Dr. Li's work primarily focuses on the synthesis of target compounds for drug discovery, with two new drugs recently approved in China.

ISBN 9783527852635
Article number 9783527852635
Media type eBook - PDF
Copyright year 2025
Publisher Wiley-VCH
Length 416 pages
Language English
Copy protection Adobe DRM