Prostate cancer treatment dates back almost treatment approaches is examined in the subse- 100years. However, in an era of rapid develop- quent chapters of this volume. ments and innovations in cancer research and Te text addresses the time-honoured h- uro-oncology, there is an increasing need to monal treatment, which has been the mainstay update our knowledge and especially to guide of prostate cancer management for some - our practice by innovations and evidence-based cades. Due to the increased diagnosis of prostate medicine. Prostate cancer is still evolving fol- cancer at earlier stages and the increased use of lowing improvements in disease detection and hormone therapy in earlier disease stages many better understanding of disease characteristics. patients will receive hormone therapy for a long Tis book addresses the current state of the art in period. Tese patients are at risk of acute and this still-developing feld and presents the reader chronic side efects of hormonal therapy. Te- with the information needed to make rational fore, the timing of initiating hormone therapy, patient decisions regarding treatment selection the type of hormone therapy and the monitoring and outcomes. of patients on long-term hormone therapy have Te growing body of knowledge regarding become crucial in the appropriate management epidemiology, pathogenesis, prevention, screen- of patients with prostate cancer. ing, diagnosis and staging is included in the frst Disease management in men with prostate half of the book.

1;Preface;5 2;International Prostate Health Council;6 3;Contents;7 4;List of Contributors;9 5;Epidemiology of Prostate Cancer;12 6;Natural History of Prostatic Carcinoma: The Pathologist's Perspective;20 7;Prognostic Factors in Prostate Cancer;36 8;The Prevention of Prostate Cancer;44 9;Prostate Cancer Screening;75 10;Diagnosis of Prostate Cancer;92 11;Does Localized Prostate Cancer Exist?;109 12;Staging of Prostate Cancer;116 13;Guidelines and Counselling for Treatment Options in the Management of Prostate Cancer;138 14;Choices for Surgery;170 15;Radiation Therapy in Prostate Cancer;186 16;Cryoablation and High- Intensity Focused Ultrasound;207 17;The Role of Hormonal Treatment in Prostate Cancer;216 18;Androgen- Independent Prostate Cancer;243 19;Prostate Cancer Treatment and Quality of Life;254 20;Europa Uomo: The European Prostate Cancer Coalition;269