RNA Trafficking and Nuclear Structure Dynamics

RNA Trafficking and Nuclear Structure Dynamics

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Over the last few years remarkable progress has been accomplished with respect to our understanding of nuclear structure and trafficking. This volume concentrates on aspects that involve or are of relevance to RNA and RNPs. Topics include fundamental advances and current problems in the structural organization of different subnuclear compartments: chromatin, nucleolus and perinucleolar compartment, Cajal bodies and gems, speckles containing splicing factors, as well as the PML bodies characteristic of ProMyelocytic Leukemia. It also describes recent progress in the dynamic aspects of RNA trafficking and in the latest technologies for live cell imaging of mRNA. The major general message of this volume is that nuclear structure is much more dynamic than previously anticipated.



Nuclear Organisation and Subnuclear Bodies
Searching for Active Ribosomal Genes
Toxic RNA in the Nucleus: Unstable Microsatellite Expression in Neuromuscular Disease
Assembly and Traffic of Small Nuclear RNPs
Intranuclear Pre-mRNA Trafficking in an Insect Model System
Photobleaching Microscopy Reveals the Dynamics of mRNA-Binding Proteins Inside Live Cell Nuclei
Imaging of Single mRNAs in the Cytoplasm of Living Cells.
ISBN 978-3-540-74265-4
Article number 9783540742654
Media type Book
Edition number Repr.
Copyright year 2007
Publisher Springer, Berlin
Length IX, 153 pages
Illustrations IX, 153 p.
Language English