Science of Synthesis: Houben-Weyl Methods of Molecular Transformations is the entirely new edition of the acclaimed reference series Houben-Weyl, the standard synthetic chemistry resource since 1909. This new edition is published in English and will comprise 48 volumes published between the years 2000 and 2008.

Science of Synthesis is a quality reference work developed by a highly esteemed editorial board to provide a comprehensive and critical selection of reliable organic and organometallic synthetic methods. This unique resource is designed to be the first point of reference when searching for a synthesis strategy.

• Contains the expertise of presently 400 leading chemists worldwide
• Critically evaluates the preparative applicability and significance of the synthetic methods
• Discusses relevant background information and provides detailed experimental procedures

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1;Science of Synthesis - Volume 40b: Amine N-Oxides, Haloamines, Hydroxylaminesand Sulfur Analogues, and Hydrazines;11.1;Title page;31.2;Imprint;51.3;Preface;61.4;Volume Editor's Preface;81.5;Overview;101.6;Table of Contents;121.7;40.2 Product Class 2: Nitroxyl Radicals (Nitroxides);261.7.1;40.2.1 Synthesis of Product Class 2;271.7.1.1;40.2.1.1 Method 1: Oxidation of Amines;271.7.1.2;40.2.1.2 Method 2: Oxidation of Hydroxylamines;281.7.1.2.1;40.2.1.2.1 Variation 1: From Hydroxylamines;281.7.1.2.2;40.2.1.2.2 Variation 2: From Nitrones;291.7.1.3;40.2.1.3 Methods 3: Other Methods;291.7.2;40.2.2 Applications of Product Class 2 in Organic Synthesis;301.7.2.1;40.2.2.1 Method 1: Alcohol Oxidation;301.7.2.2;40.2.2.2 Method 2: Controlled Radical Polymerization;311.7.2.3;40.2.2.3 Method 3: Radical Carboaminoxylations;321.8;40.3 Product Class 3: Amine N-Oxides;361.8.1;40.3.1 Synthesis of Product Class 3;411.8.1.1;40.3.1.1 Method 1: Reaction of Hydroxylamines with Alkylating Agents;411.8.1.2;40.3.1.2 Method 2: Oxidation of Tertiary Amines;421.8.1.2.1;40.3.1.2.1 Variation 1: Using Hydrogen Peroxide;431.8.1.2.2;40.3.1.2.2 Variation 2: Using Alkyl Hydroperoxides;461.8.1.2.3;40.3.1.2.3 Variation 3: Using Peracids;491.8.1.2.4;40.3.1.2.4 Variation 4: Using Molecular Oxygen;531.8.1.2.5;40.3.1.2.5 Variation 5: Using Ozone;531.8.1.2.6;40.3.1.2.6 Variation 6: Using Oxaziridines;541.8.1.2.7;40.3.1.2.7 Variation 7: Using Dimethyldioxirane;551.8.1.2.8;40.3.1.2.8 Variation 8: Using Magnesium Monoperoxyphthalate;561.8.1.2.9;40.3.1.2.9 Variation 9: Using Hypofluorous Acid--Acetonitrile Complex;561.8.1.2.10;40.3.1.2.10 Variation 10: Using Biomimetic Hydroperoxides;561.8.1.2.11;40.3.1.2.11 Variation 11: Using Enzymatic Transformations;581.8.1.3;40.3.1.3 Method 3: Reverse Cope Cyclization;591.8.1.4;40.3.1.4 Method 4: Synthesis of Enamine N-Oxides;661.9;40.4 Product Class 4: N-Haloamines;741.9.1;40.4.1 Product Subclass 1: N-Fluoroamines;751.9.1.1;40.4.1.1 Synthesis of Product Subclass 1;751.9.1.1.1;40.4.1.1.1 Method 1: Synthesis of N-Fluoroalkanamines;751.9.1.1.1.1;40.4.1.1.1.1 Variation 1: From Imines;751.9.1.1.1.2;40.4.1.1.1.2 Variation 2: From Amides;761.9.1.1.1.3;40.4.1.1.1.3 Variation 3: From Amines;771.9.1.1.2;40.4.1.1.2 Method 2: Synthesis of Acyclic N-Fluorodialkylamines;781.9.1.1.2.1;40.4.1.1.2.1 Variation 1: From Imines;781.9.1.1.2.2;40.4.1.1.2.2 Variation 2: From Secondary Amines;781.9.1.1.3;40.4.1.1.3 Method 3: Synthesis of 1-Fluoroaziridines;791.9.1.1.4;40.4.1.1.4 Method 4: Synthesis of Higher N-Fluoroazacyclanes;821.9.2;40.4.2 Product Subclass 2: N-Chloroamines;821.9.2.1;40.4.2.1 Synthesis of Product Subclass 2;821.9.2.1.1;40.4.2.1.1 Method 1: Synthesis of N_Chloroalkanamines;821.9.2.1.1.1;40.4.2.1.1.1 Variation 1: From Primary Amines Using Chlorine;821.9.2.1.1.2;40.4.2.1.1.2 Variation 2: From Primary Amines Using a Metal Hypochlorite;831.9.2.1.1.3;40.4.2.1.1.3 Variation 3: From Primary Amines Using tert-Butyl Hypochlorite;841.9.2.1.1.4;40.4.2.1.1.4 Variation 4: From Primary Amines Using N-Chlorosuccinimide;841.9.2.1.1.5;40.4.2.1.1.5 Variation 5: From N-(Trimethylsilyl)ethanamine;851.9.2.1.2;40.4.2.1.2 Method 2: Synthesis of Acyclic N-Chlorodialkylamines;851.9.2.1.2.1;40.4.2.1.2.1 Variation 1: From Secondary Amines Using Metal Hypochlorites;851.9.2.1.2.2;40.4.2.1.2.2 Variation 2: From Secondary Amines Using tert-Butyl Hypochlorite;881.9.2.1.2.3;40.4.2.1.2.3 Variation 3: From Secondary Amines Using N-Chloroamides;881.9.2.1.2.4;40.4.2.1.2.4 Variation 4: From (Trialkylsilyl)amines;891.9.2.1.2.5;40.4.2.1.2.5 Variation 5: From Imines and Alkenes;901.9.2.1.2.6;40.4.2.1.2.6 Variation 6: From Aziridines;911.9.2.1.3;40.4.2.1.3 Method 3: Synthesis of 1-Chloroaziridines;911.9.2.1.3.1;40.4.2.1.3.1 Variation 1: Using Chlorine;921.9.2.1.3.2;40.4.2.1.3.2 Variation 2: Using a Metal Hypochlorite;921.9.2.1.3.3;40.4.2.1.3.3 Variation 3: Usi