Science of Synthesis: Houben-Weyl Methods of Molecular Transformations is the entirely new edition of the acclaimed reference series Houben-Weyl, the standard synthetic chemistry resource since 1909. This new edition is published in English and will comprise 48 volumes published between the years 2000 and 2008.

Science of Synthesis is a quality reference work developed by a highly esteemed editorial board to provide a comprehensive and critical selection of reliable organic and organometallic synthetic methods. This unique resource is designed to be the first point of reference when searching for a synthesis strategy.

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1;Science of Synthesis - Volume 34: Fluorine;11.1;Title page;31.2;Imprint;51.3;Preface;61.4;Volume Editor's Preface;81.5;Overview;101.6;Table of Contents;121.7;Introduction;221.8;34.1 Product Class 1: Fluoroalkanes;321.8.1;34.1.1 Synthesis by Substitution of Hydrogen;421.8.1.1;34.1.1.1 Method 1: Direct Fluorination with Elemental Fluorine;421.8.1.2;34.1.1.2 Method 2: Reaction with Selectfluor;501.8.1.3;34.1.1.3 Method 3: Reaction with Xenon Difluoride;531.8.1.4;34.1.1.4 Method 4: Reaction with Organic Hypofluorites;541.8.1.5;34.1.1.5 Method 5: Reaction with Cesium Fluoroxysulfate;561.8.1.6;34.1.1.6 Method 6: Reaction with Hydrogen Fluoride/Pyridine and Nitrosonium Tetrafluoroborate;581.8.2;34.1.2 Synthesis by Substitution of Metals;601.8.2.1;34.1.2.1 Method 1: Synthesis from Organosilanes;611.8.2.2;34.1.2.2 Method 2: Synthesis from an Organothallium Compound;631.8.2.3;34.1.2.3 Method 3: Synthesis from Organomercury Compounds;641.8.2.4;34.1.2.4 Method 4: Synthesis from Organomagnesium Compounds;651.8.2.5;34.1.2.5 Method 5: Synthesis from Organolithium Compounds;661.8.2.5.1;34.1.2.5.1 Variation 1: Using Molecular Fluorine;661.8.2.5.2;34.1.2.5.2 Variation 2: Using Perchloryl Fluoride;671.8.3;34.1.3 Synthesis by Substitution of Carbon Functionalities;701.8.3.1;34.1.3.1 Method 1: Synthesis from Alkanecarboxylates Using Fluorine;701.8.3.2;34.1.3.2 Method 2: Synthesis from Alkanecarboxylic Acids;711.8.3.2.1;34.1.3.2.1 Variation 1: Using Titanium(IV) Oxide/Silver(I) Fluoride;711.8.3.2.2;34.1.3.2.2 Variation 2: Using Xenon Difluoride;721.8.3.2.3;34.1.3.2.3 Variation 3: Using Bromine Trifluoride;741.8.3.2.4;34.1.3.2.4 Variation 4: Using Triethylamine Trihydrofluoride;751.8.3.3;34.1.3.3 Method 3: Synthesis from Cyclopropanes;751.8.4;34.1.4 Synthesis by Substitution of Heteroatoms;781.8.4.1;34.1.4.1 Synthesis by Substitution of a Halogen;781.8.4.1.1;34.1.4.1.1 Method 1: Substitution of Primary Halides;781.8.4.1.1.1;34.1.4.1.1.1 Variation 1: Using Metal Fluorides;781.8.4.1.1.2;34.1.4.1.1.2 Variation 2: Using Hydrogen Fluoride Complexes;811.8.4.1.1.3;34.1.4.1.1.3 Variation 3: Using Tetraalkylammonium Fluorides;821.8.4.1.1.4;34.1.4.1.1.4 Variation 4: Using Fluorosilicate Derivatives;831.8.4.1.2;34.1.4.1.2 Method 2: Substitution of Secondary Halides;831.8.4.1.2.1;34.1.4.1.2.1 Variation 1: Using Metal Fluorides;841.8.4.1.2.2;34.1.4.1.2.2 Variation 2: Using Hydrogen Fluoride Complexes;861.8.4.1.3;34.1.4.1.3 Method 3: Substitution of Tertiary Halides;871.8.4.1.3.1;34.1.4.1.3.1 Variation 1: Using Metal Fluorides;871.8.4.1.3.2;34.1.4.1.3.2 Variation 2: Using Base--Hydrogen Fluoride Complexes;881.8.4.1.3.3;34.1.4.1.3.3 Variation 3: Using Silver(I) Tetrafluoroborate;881.8.4.1.3.4;34.1.4.1.3.4 Variation 4: Using Ruthenium Complexes;891.8.4.2;34.1.4.2 Synthesis by Substitution of Hydroxy Groups in Alcohols;921.8.4.2.1;34.1.4.2.1 Method 1: Reaction with Fluoro-.4-sulfanes;931.8.4.2.1.1;34.1.4.2.1.1 Variation 1: With N,N-Diethylaminosulfur Trifluoride;971.8.4.2.1.2;34.1.4.2.1.2 Variation 2: With N,N-Bis(2-methoxyethyl)aminosulfur Trifluoride (Deoxo-Fluor);1291.8.4.2.1.3;34.1.4.2.1.3 Variation 3: With Morpholinosulfur Trifluoride;1321.8.4.2.1.4;34.1.4.2.1.4 Variation 4: With N,N-Dimethylaminosulfur Trifluoride;1341.8.4.2.1.5;34.1.4.2.1.5 Variation 5: With Other Dialkylaminofluoro-.4-sulfanes;1341.8.4.2.1.6;34.1.4.2.1.6 Variation 6: With Sulfur Tetrafluoride;1351.8.4.2.1.7;34.1.4.2.1.7 Variation 7: With Alkoxysulfur Trifluorides;1371.8.4.2.2;34.1.4.2.2 Method 2: Reaction with Selenium Tetrafluoride;1381.8.4.2.3;34.1.4.2.3 Method 3: Reaction with Fluorophosphoranes;1391.8.4.2.3.1;34.1.4.2.3.1 Variation 1: With Difluoro(triphenyl)phosphorane;1401.8.4.2.3.2;34.1.4.2.3.2 Variation 2: With Trifluoro(diphenyl)phosphorane;1401.8.4.2.3.3;34.1.4.2.3.3 Variation 3: With Tetrafluoro(phenyl)phosphorane;1401.8.4.2.4;34.1.4.2.4 Method 4: Reaction with Fluo