Current evidence indicates that over two-thirds of mooddisorders pursue a recurrent or chronic course. Yet much ofthe progress recorded in the field of mood disorders andtheir treatment has been in research into the acute phase ofthe illness. Hence there is a need for a volume thatspecifically addresses the special clinical problemsencountered inthe recurrent forms of these disorders.The various chapters of this book embrace a wide range oftopics, including etiology, course, and long-term treatment,integrative reviews, results of recent investigations, andclinical reports. In this respect, the contributions reflectcurrentconcepts, research, and clinical practice. We haveendeavored to build a bridge between neurobiology andpsychology and have covered both the psychotherapeutic andthe psychopharmacologic aspects of mood disorders.

Etiologic Aspects

Toward a Psychobiology of Affective Recurrences: Interaction of Biological and Psychological Factors
New Genetic Findings in Recurrent Mood Disorders
Recent Findings on Thyroid Function in Depression
Cognitive Aspects of Depression: An Experimental Study
Variability of Cognitive Patterns in Subjects with Mood Disorder
Personality and Depression
Aggressive Behaviour and Hostility in Depression: Clinical Aspects
Course and Outcome
Course as Classifier for Depression
Course and Outcome: Definitional Dilemmas
Bipolar Disorders in Prepubertal Children
Bipolar Disorder in Adolescence
Diagnosis, Clinical Assessment, and Treatment of Late-Life Depression
Recurrent Major Depression: Catamnestic Evaluation of Inpatients
Psychotic Mixed State: Clinical-Anamnestic and Familial Comparisons with Nonpsychotic Mixed, Psychotic Manic, and Schizoaffective Disorders
Heterogeneity of Course and Outcome in Subjects with a Cross-Sectional Diagnosis of Schizoaffective Disorder
Old and New Treatments and Prophylaxis
Testing Efficacy and Safety of Long-Term Treatment in Manic-Depressive Illness: Past and Present Problems
The Prophylaxis of Unipolar Depression
Maintenance Therapies in Recurrent Depression: Psychotherapy and Combined Treatment
Lithium Treatment: Relationship Between Relapses and Personality Disorders
Effects of Lithium on Information Processing: Evidence from Partial Responders and Nonresponders
Chronic Lithium Salt Treatment and Calcium Metabolism
Amiloride and Severe Lithium-Induced Nephrogenic Diabetes Insipidus
New Pharmacological Aspects of Rubidium Salts
Rubidium - 20 Years On
Biochemical and Physiological Guidelines for Long-Term Rubidium Therapy
Rubidium Shows Different Effects from Lithium on Phosphatidylinositol Metabolism in a Cell Line of Human Neuroblastoma
Influences of Rubidium and Lithium on Cyclic AMP Formation in Rat Brain
Electrolytes, Renal Function, and Rubidium Chloride Therapy Side Effects
Antidepressive Action of Rubidium
Treatment of Depressive Disorders with Rubidium Chloride
Clinical Investigations on the Efficacy and Tolerability of Rubidium Chloride
Rubidium Chloride in Recurrent Depression: Clinical and Biological Correlates
Rubidium Chloride in Chronic Mood Disorders
Rubidium Chloride Versus Imipramine: A Double-Blind Study
Psychotherapeutic Problems in Chronic and Resistant Depressions
Bright Light Treatment of Seasonal Affective Disorder and Nonseasonal Bipolar and Unipolar Affective Syndromes.