This book, now in its revised and updated third edition, provides a state of the art overview of fMRI and its use in clinical practice. Experts in the field share their knowledge and explain how to overcome diverse potential technical barriers and problems. Starting from the very basics on the origin of the BOLD signal, the book covers technical issues, anatomical landmarks, methods of statistical analysis, and special issues in various clinical fields. Comparisons are made with other brain mapping techniques and their combined use with fMRI is also discussed. Existing chapters have been updated and new chapters have been added in order to account for new applications, further clinical fields and methods, e.g. resting state fMRI.

Based on the clinical focus, this book will be of great value for Neuroradiologists, Neurologists, Neurosurgeons but also Researchers in Neuroscience.

PART I BASICS Chapter 1 Introduction

Chapter 2 Neuroanatomy and Cortical Landmarks
Chapter 3 The Electrophysiological Background of the fMRI Signal
Chapter 4 High-Field fMRI
Chapter 5 Resting State fMRI: Preclinical Foundations
Chapter 6 Spatial Resolution of fMRI Techniques
Chapter 7 Acquisition Aspects of Functional and Clinical Arterial Spin Labeling
Chapter 8 fMRI Data Analysis Using SPM
Chapter 9 Meta-Analyses in Basic and Clinical Neuroscience: State of the Art and Perspective.- PART II CLINICAL APPLICATIONS Chapter 10 Special Issues in fMRI Involving Children
Chapter 11 Multimodal Brain Mapping in Patients with Early Brain Lesions
Chapter 12 Combining Transcranial Magnetic Stimulation with (f)MRI
Chapter 13 Simultaneous EEG and fMRI Recordings (EEG-fMRI)
Chapter 14 Imaging Epileptic Seizures Using fMRI
Chapter 15 The Functional Anatomy of Speech Processing: From Auditory Cortex to Speech Recognition and Speech Production
Chapter 16 Mapping of Recovery from Poststroke Aphasia: Comparison of PET and fMRI
Chapter 17 Use of fMRI Language Lateralization for Quantitative Prediction of Naming and Verbal Memory Outcome in Left Temporal Lobe Epilepsy Surgery
Chapter 18 Preoperative Blood Oxygen Level-Dependent (BOLD) Functional Magnetic Resonance Imaging (fMRI) of Motor and Somatosensory Function
Chapter 19 Resting State Functional MRI for Presurgical Planning
Chapter 20 Functional Magnetic Resonance-Guided Resection of Intra-Axial Brain Tumors
Chapter 21 Direct Cortical Stimulation and fMRI
Chapter 22 Modeling Connectivity in Health and Disease: Examples from the Motor System
Chapter 23 Resting State fMRI in Multiple Sclerosis
Chapter 24 The Perirhinal, Entorhinal, and Parahippocampal Cortices and Hippocampus: An Overview of Functional Anatomy and Protocol for Their Segmentation in MR Images
Chapter 25 Brain Network Functional Connectivity in Alzheimer's Disease and Frontotemporal Dementia
Chapter 26 fMRI in Parkinson's Disease
Chapter 27 Incidental Findings in Neuroimaging Research: Ethical Consideration