Contemporary Bone Marrow Transplantation

Contemporary Bone Marrow Transplantation

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Bone Marrow transplantation or Hematopoietic stem cell transplantation is a life saving procedure in a number of diseases,hematological and non hematological, which fail alternative medical management or have no other treatment options. It has transformed the lives of thousands of patients and their families around the world battling with fatal or debilitating diseases.There are many unique aspects of bone marrow transplantation which makes it very different from solid organ transplants.  There is an enormous amount of research going on in this field both at clinical and basic science levels.With the rapidly changing world and field of transplantation, there is a need for an authoritative and up to date resource for transplant professionals.
This book titled Contemporary Bone Marrow Transplantation aims to be a reference text comprehensively covering  various facets of hematopoietic stem cell transplants with latest insights about the technique and basic sciencebehind it . The book is the product of collective effort of transplant professionals round the world, and will reflect their experience as well as the current standard of care practices in Stem cell transplantation.The book will be divided into different sections focusing on the basic science of bone marrow transplant, the technical aspects of the procedure itself and the supportive care of transplant patients.There will also be a section each on epidemiology, upcoming trends and also case studies , which will discuss real case scenarios from the experience of the authors, to illustrate the practical challenges in managing bone marrow transplant recipients.


History of Bone Marrow Transplantation
Section I: Biology of Bone Marrow Transplantation-At the Benchside
Hematopoietic Stem cell Biology-Basics
Innovations in Understanding Hematopoietic Transplant Biology
HLA in Stem Cell Transplant-Finding the Match
Therapeutic Use of Hematopoietic Stem cells-Benign and Malignant Diseases
Biology of Graft Versus Host Disease
Section II: Bone Marrow Transplantation-the Procedure
Types of Bone Marrow Transplant and Indications
Allogeneic Stem Cell Transplant-Overview
Haploidentical Stem Dell Transplantation- a Game Changer?
Autologous Stem Cell Transplant
Donor Selection for Stem Cell Transplant
Conditioning in Bone Marrow Transplant
Immunosuppressive Therapy
Transplant Pharmacology
Radiation Therapy in HSCT
Graft Versus Host Disease
Graft Failure in Stem Cell Transplant
Immunomodulation in Bone Marrow Transplantation
Pre-transplant Evaluation of Recipient and Donor
Setting up the Bone Marrow Transplantation Unit
Section III: Handling the Stem Cells
Hematopoietic Stem Cell Collection Techniques
Ex Vivo Manipulation of Stem Cells
Cryopreservation in HSCT
Section IV: Supportive Care in Bone Marrow Transplantation
Acute Complications in HSCT
Infections in Bone Marrow Transplant Patients
Blood Product Support in HSCT
Nutritional Issues in HSCT Patients
Psycho-social Issues in Bone Marrow Transplantation
Pediatric Bone Marrow Transplantations
Special Challenges
Long Term Follow Up and Chronic Complications in Post Stem Cell Transplant Patients
Section V: Epidemiology of Bone Marrow Transplantation
Bone Marrow Transplant Data Management and Registries
Outcomes of Bone Marrow Transplantation
Section VI: Newer Trends
Future of Hematopoietic Stem Cell Transplant
Cellular Therapy
Use of Cellular Therapy in Cancer and Infections
Section VII: Case Studies in Bone Marrow Transplantation.
ISBN 978-3-030-36357-4
Medientyp Buch
Copyrightjahr 2021
Verlag Springer, Berlin
Umfang XVII, 781 Seiten
Sprache Englisch