This book provides a comprehensive and practical guide for the safe and efficient management of patients with intrinsic brain tumors and medically intractable epilepsy. It presents in an easily understandable way the preoperative evaluation of these patients, starting from the clinical interpretation of conventional anatomical MR imaging and analyses the clinical significance of newer MR based imaging techniques such as diffusion and perfusion imaging.

It demonstrates with clarity the role of MR spectroscopy and fractional anisotropy and diffusion tensor imaging in the preoperative assessment of these patients and how this data can be incorporated into the surgical planning.

This book is aimed at neurosurgeons, neuroradiologists, neurologists, and epileptologists, and may also be of interest to neuropsychologists, neurophysiologists, radiation oncologists, and medical physicists.

Preoperative Evaluation: Non-invasive Methods.- Neurological examination & semiology

Interpretation of conventional anatomical MRI
Interpretation of proton MR spectroscopic imaging?
Fractional Anisotropy and Diffusion Tensor Imaging as preoperative tools
Functional MRI
Nuclear medicine as a preoperative tool
PET CT/MRI as a preoperative tool
Magneto-Encephalography and Magnetic Source Imaging as preoperative tools
Surface Encephalography and video-Encephalography
High-density Encephalography as preoperative tool
Transcranial magnetic source stimulation as preoperative tool
Preoperative neuropsychological evaluation
Preoperative Evaluation: Invasive Methods
Invasive Electroencephalography with subdural/depth electrodes
Stereo-Encephalography
Extra-operative cortical stimulation and mapping
Surgical Management:General considerations
Intraoperative electrophysiological monitoring
Awake procedures for cortical/subcortical mapping and monitoring
Postoperative evaluation and follow-up.- Surgical Management: Epilepsy Surgical Procedures
Neocortical resections
Anterior temporal lobectomy and amygdalo-hippocampectomy
Selective amygdalo-hippocampectomy
Multiple subpial transections
Corpus callosotomy
Hemisherotomy
Vagus nerve stimulation
Deep brain stimulation
Cortical stimulation
G-knife in epilepsy
Cyberknife in epilepsy
Novel focal treatment modalities in epilepsy
Surgical Management: Intrinsic Tumor Surgical Procedures
Surgical resection techniques of frontal lobe tumors
Surgical resection techniques of temporal lobe tumors
Surgical resection techniques of central area tumors
Surgical resection techniques of parietal lobe tumors
Surgical resection techniques of occipital lobe tumors
Surgical resection techniques of insular tumors
Adjuvant treatment for intrinsic brain tumors
Local interstitial chemotherapy
Local interstitialbrachytherapy
External radiation therapy
Adjuvant stereotactic radiosurgery
Systematic chemotherapy in intrinsic brain tumors
Novel adjuvant focal therapies
Monitoring for tumor recurrence
Management of tumor recurrence.