Cancer is a very aggressive disease and currently it has been considered a challenge to oncologists and cancer patients worldwide. Nowadays, several therapeutic strategies had improved toward last decades. Surgery is many times still the best curative treatment, mainly in early stage disease. However, Radiotherapy and chemotherapy acquired a main role in this scenario. Target therapies were introduced for medical oncology practice and are demonstrating a hallmark of a new era in cancer treatment. More recently, immunotherapy has been considered the novel cornerstone in cancer treatment. The 2^nd edition of the International Manual of Oncology Practice (iMOP) emerged after the great success of the iMOP 1^st edition as a reference for medical oncologists and medical residents in the field. In this edition, several chapters were revised and its addresses from the molecular issues of cancer sciences to the clinical practice in medical oncology. In addition, multiple choice questions and clinical cases were included in the main chapters in order to improve the reader learning. The book focuses systemic treatments in many areas of medical oncology, such as breast cancer, gastrointestinal, thoracic, urological oncology, head and neck tumors, bone tumors, sarcomas and palliative care. The topics herein discussed will provide the readers a step forward in the medical oncology practice understanding and give facilities for help in cancer patient treatments.   

<p>1</p> <p>Cancer screening and epidemiology</p> <p>R.A. De Mello</p> <p>ramello@ualg.pt or ramondemello@doctors.org.uk </p> <p>UALG, Portugal</p> <p>2</p> <p>Cancer stem cells</p> <p>José Bragança</p> <p>jebraganca@ualg.pt  </p> <p>UALG, Portugal</p> <p>3</p> <p>Apoptosis</p> <p>Richard Hill</p> <p>richard.hill@port.ac.uk</p> <p>UALG, Portugal</p> <p>4</p> <p>Angiogenesis</p> <p>Patrícia Madureira</p> <p>pamadureira@ualg.pt</p> <p>UALG, Portugal</p> <p>5</p> <p>Genetic basis of metastasis</p> <p>Mehmet Gunduz</p> <p>mehmet.gunduz@gmail.com</p> <p>Turgut Ozal University, Turkey</p> <p>6</p> <p>Anti-cancer Drugs</p> <p>Wolfgang Link</p> <p>walink@ualg.pt</p> <p>UALG, Portugal </p> <p>7</p> <p>Immuno-oncology</p> <p>Pedro Madureira</p> <p>ramondemello@gmail.com </p> <p>ICBAS Portugal</p> <p>8</p> <p>Health Econimics</p> Nelson Teich<p></p> <p>nelsonteich@americasoncologia.com.br </p> <p>Américas Oncologia, Rio de Janeiro, Brazil</p> <p><b>PART II - SOLID TUMORS</b></p> <p><b>THORACIC</b></p> <p>9</p> <p>Non-Small Cell Lung cancer</p> <p>A. Tantraworasin</p> <p>ohm_med@hotmail.com</p> <p>Chiang Mai University, Thailand</p> <p>10</p> <p>Small cell lung cancer</p> <p>A. Tantraworasin</p> <p>ohm_med@hotmail.com</p> <p>Chiang Mai University, Thailand</p> <p>11</p> <p>Mesothelioma</p> <p>Vangelis Karamitrousis</p> <p>v-a-g-@hotmail.com</p> <p>Alexandroupolis, Greece</p> <p>12</p> <p>Thymus</p> <p>Hakaru Tadokoro</p> <p>ramondemello@gmail.com</p> <p>UNIFESP, Brazil</p> <p>BREAST</p> <p> 13</p> <p>Breast </p> <p>Ines Monteiro</p> <p>ines.pcmonteiro@gmail.com </p> <p>Lausanne, Switezerland</p> <p><b>GASTROINTESTINAL</b></p> <p>14</p> Oesophageal<p></p> <p>Karima Oualla</p> karimarauf@hotmail.com <p></p> <p>Fes, Marroco</p> <p>15</p> <p>Gastric</p> <p>Luis Castelo-Branco</p> <p>luismocb@hotmail.com</p> <p>Faro, Portugal </p> <p>16</p> <p>Colon</p> <p>Nora Forones</p> <p>noraforones@gmail.com</p> <p>UNIFESP, Brazil</p> <p>17</p> <p>Rectal</p> <p>JInhui Zhu</p> <p>ramondemello@gmail.com  </p> <p>China</p> <p>18</p> <p>Anal Canal Cancer</p> Hakaru Tadokoro<p></p> <p>ramondemello@gmail.com </p> <p>UNIFESP, Brazil</p> <p>19</p> <p>Small intestine</p> <p>Pedro Aguiar Jr</p> <p>pnajpg@hotmail.com </p> Santo André, Brazil<p></p> <p>20</p> <p>Liver Cancer</p> <p>R. A. DE Mello</p> <p>ramondemello@gmail.com</p> <p>UNIFESP, Brazil</p> <p>21</p> <p>Pancreatic Cancer</p> <p>George Antoniou</p> <p>dr.antoniou@gmail.com </p> London, UK<p></p> <p><b>GYNECOLOGICAL TUMORS</b></p> <p>22</p> <p>Ovarian </p> <p>Renata Justa </p> <p>renatajusta@gmail.com </p> <p>ICC, Brazil</p> <p>23</p> <p>Cervical</p> <p>Alvaro Henrique Ingles Garces</p> <p>alvarohenriq@yahoo.com.br </p> <p>INCA, Brazil</p> <p>24</p> <p>Vagina</p> <p>Nikolaou Michail</p> <p>nikolaoumike@hotmail.com </p> <p>Larissa, Greece</p> <p>25</p> <p>Gestacional trophoblastic disease</p> <p>Donald Peter Goldstein</p> <p>DGOLDSTEIN@partners.org </p> <p>Boston, MA, USA </p> <p><b>GENITO-URINARY</b></p> 26<p></p> <p>Prostate Cancer</p> <p> </p> <p>Arlindo Ferreira</p> <p>ajrsferreira@gmail.com </p> <p>Lisboa, Portugal</p> <p>27</p> <p>Renal Cell Carcinoma</p> Fernando Nunes<p></p> <p>fernando.nunes@clion.com.br </p> <p>Salvador, Brazil </p> <p>28</p> <p>Urothelial Cancer</p> Ramy F. Youssef <p></p> <p>ryaacoub@uci.edu </p> <p>California, USA</p> <p>29</p> <p>Germ-Cell Tumors</p> <p>Giannis Mountzios</p> <p>gmountzios@gmail.com </p> Athens, Greece<p></p> <p>29.1</p> <p>Penile Cancer</p> <p>Nikolaos Tsoukalas </p> <p>tsoukn@yahoo.gr </p> <p>London, UK</p> 30<p></p> <p>Squamous Head and neck</p> Jean-Pascal Machiels<p></p> <p> </p> <p>jean-pascal.machiels@uclouvain.be </p> <p>Brussels, Belgium</p> <p>31</p> <p>Thyroid cancer</p> Washington Luiz<p></p> <p>wwgois@gmail.com </p> <p>Fortaleza, Brazil</p> <p>32</p> <p>Parotid Gland Tumors</p> <p>José Aurillo Rocha</p> <p>jaurillo@hotmail.com </p> Fortaleza, Brazil<p></p> <p><b>SKIN, SOFT TISSUE, BONE, GIST AND ENDOCRINE</b></p> 33<p></p> <p>Melanoma</p> Paolo Ascierto<p></p> <p>paolo.ascierto@gmail.com </p> <p>Napoli, Italy</p> <p>34</p> <p>Soft Tissue Sarcomas</p> <p>Carlos Marcio</p> <p>carlossmarcio@gmail.com </p> <p>Fortaleza, Brazil</p> <p>35</p> <p>Bone Sarcomas</p> <p>Hakaru Tadokoro</p> <p>ramondemello@gmail.com</p> <p>UNIFESP, Brazil</p> <p>36</p> <p>GIST</p> <p>R. A. De Mello</p> <p>ramondemello@gmail.com</p> <p>Brazil/Switzerland</p> <p>37</p> <p>NET</p> <p>Yim KL</p> <p>yimkl2000@hotmail.com </p> <p>Cardiff, UK</p> <p>38</p> <p>Primary brain tumor</p> <p>Hakaru Tadokoro</p> <p>ramondemello@gmail.com</p> <p>UNIFESP, Brazil</p> <p><b>PART III - HEMATO-ONCOLOGY</b></p> <p>39</p> <p>Acute Lymphoblastic Leukemia</p> <p>Eddy Supriyadi</p> <p>e.supriyadi@gadjahmada.edu   </p> <p>Indonesia </p> <p>40</p> <p>Myelodisplastic Syndrome</p> <p>Ronald Feitosa</p> <p>ronaldfpinheiro@uol.com.br </p> <p>Fortaleza, Brazil</p> <p><b>PART IV - PALLIATIVE CARE AND SUPPORTIVE CARE</b></p> <p>41</p> <p>Metabolic disturbance/paraneoplasic syndromes</p> <p>Carmélia Barreto</p> <p>carmeliabarreto@gmail.com </p> <p>Sao Paulo, Brazil</p> 42<p></p> <p>Spinal medular compression</p> Hakaru Tadokoro<p></p> <p>ramondemello@gmail.com</p> São Paulo, Brazil<p></p> <p>43</p> <p>Superior vena cava syndrome</p> <p>Maria Tolia </p> <p>mariatolia1@gmail.com    </p> <p>Larissa, Greece</p> <p>44</p> <p>Febrile neutropenia</p> <p>Bora Lim</p> <p>naborala@gmail.com</p> <p>Texas, USA</p> <p>45</p> <p>Chemotherapy-Induced Nausea and Vomiting</p> <p>Rudolph M. Navari</p> <p>rmnavari@gmail.com</p> <p>Indiana University School of Medicine South Bend, USA</p> <p>46</p> <p>Asthenia</p> <p>F. Koinis</p> <p>phillipkoinis@gmail.com</p> <p>Athens, Greece</p> <p>47</p> <p>Oncological pain</p> <p>R.A. De Mello</p> <p>ramondemello@gmail.com</p> <p>UALG, Portugal</p> <p>48</p> <p>Bone Metastases</p> <p>Arlindo Rebelo-Ferreira</p> <p>arjsferreira@gmail.com  </p> <p>Lisbon, Portugal</p> <p>49</p> <p>Brain metastasis</p> <p>Tiago Pádua Costa</p> <p>tiagopadua1@hotmail.com</p> <p>São Paulo, Brazil</p> <p>50</p> <p>Palliative care</p> <p>Débora Galdêncio</p> <p>debora_galgencio@yahoo.com.br</p> <p>Manaus, Brazil</p> <p> </p><p> </p><p><b> </b></p>