1. Introductions of Nucleic Acid-based Nanomaterials<br>2. The methods to Improve the Stability of Framework Nucleic Acid-based Nanomaterials <br>3. Framework Nucleic Acid-Based Nanomaterials: A Promising Vehicle for Small Molecular Cargos<br>4. The Application of Framework Nucleic Acid-Based Nanomaterials in the Treatment of Mitochondrial Dysfunction<br>5. Regeneration of Bone-related Diseases by Nucleic Acid-Based Nanomaterials: Perspectives from Tissue Regeneration and Molecular Medicine<br>6. In situ Fluorescence Imaging and Biotherapy of Tumor Based on Hybridization Chain Reaction<br>7. Application and Prospects of Framework Nucleic Acid-Based Nanomaterials in Tumor Therapy<br>8. Application of Framework Nucleic Acid-Based Nanomaterials in the Treatment of Endocrine and Metabolic Diseases<br>9. The Antibacterial Applications of Framework Nucleic Acid-Based Nanomaterials: Current Progress and Further Perspectives<br>10. Framework Nucleic Acid Nanomaterials-based Therapy for Osteoarthritis: Progress and Prospects<br> <br>