Readers will discover the relatively new and rapidly growing field of regenerative surgery and fat grafting, valuable for numerous plastic surgery, reconstructive, and aesthetic/cosmetic essentials.

Though many books have covered specific areas or topics in regenerative surgery, the market lacks a work that tackles the full spectrum of regenerative surgery and its clinical application. This book responds to that need and presents chapters written by the best: world-renowned surgeons in their field.

After an introduction that reflects basic research, most of the book focuses on clinical experience as it relates to applied techniques of processing fat and on the different uses from head to toe. Readers will learn about the history of regenerative surgery, important definitions and background information, and the evidence supporting the use of regenerative surgery. Practitioners will also find valuable guidance regarding the application of stem cells, evaluation of patient needs, and operative techniques for fat transfer. Subsequent chapters address topics such as graft types, the skin, wound healing, scar treatment, osteoarthritis, burns, scleroderma, hair rejuvenation, facial enhancement combined with facelift, chin augmentation with fat, and breast argumentation or reconstruction with fat. Particular attention is paid to gluteal augmentation with fat, body contouring, genital male and female rejuvenation, and upper and lower extremity regenerative surgery. Surgical anatomy and complications treatment and prevention were emphasized when applied. This resulted is two volumes that encompass 114 chapters, with multiple figures, and video clips, written by 242 authors (including 72 female colleagues) from five continents.

Highly informative and carefully structured, this book provides invaluable insight for beginners and experienced plastic surgeons alike, while benefitting advanced surgeons, specialists, and undergraduate and graduate students. 

Part I. Introductory Part

1. Evolving of concepts in fat grafting and Regenerative Surgery
2. The Era of regenerative surgery
3. Regenerative Surgery: Definitions and Background
4. Current status on regenerative surgery
5. Fluid balance, electrolytes, and anesthetic options in regenerative surgery and fat grafting
6. Adipose Tissue Transplantation: Autologous versus cryopreserved (Frozen) versus heterologous. Present and future of fat transfer
7. Comparison between fat and fillers
Part II. Stem Cells and Clinical Path
8. Features and biological properties of different adipose tissue based products. Milli-, Micro-, Emulsified (Nano-) fat, SVF and AD-multipotent mesenchymal stem cells
9. Regenerative technologies and Adipose derived  stem cells (ADSCs): regulatory, ethical and technical updates
10. Stem Cell Research, Concepts, and Emerging Technologies
11. Stem cells and their clinical applications
12. Fat grafting, tissue banking and adipose stem celltherapies - European regulatory status in 2021
Part III. Operative Techniques for Fat Grafting
13. Aesthetic Lipofilling: Trends, Patient needs and Assessment
14. New perspective in Regenerative Surgery: The Acellular Adipose Matrix
15. New strategies in Regenerative Medicine: The Bio-Active Composite Grafts
16. Injectable Tissue Replacement and Regeneration- A New Standardized Fat Grafting Technique
17. Novel strategies to improve graft survival and retention
18. Impact of age, gender, body mass index, harvesting site, suction pressure, smoking, Diabetes, Systemic Lupus and other diseases on the regenerative properties of the grafted adipose tissue
19. Fat Processing Methods
20. Classification of Safe Autologous Fat Grafting: Quantity and Location Site
21. Complications in Regenerative and Fat Transfer Surgery: Pathophysiology and Management with Technical Tips to Reduce Risk
22. Fat grafting and Fat embolism. How to prevent, diagnose and treat
23. Potentials and Limitations of the role of platelet rich plasma (PRP) in lipofilling. An evidence based approach
24. The Role of Nurses in Fat Grafting Procedures: Planning, Preparation, and Implementation
Part IV. Regenerative Surgery: Reconstructive Areas of Application
25. Fat grafting as plastic surgeons' best friend: solving complex reconstructions problems with simple regenerative solutions
26. Treatment of radiation-induced rectovaginal fistula: Safety and efficacy of fat grafting and stromal-vascular fraction injections
27. Treatment of fibrotic radiotherapy damages in head & neck with fat grafting
28. Vampire scar: outpatient quality improvement of scar regeneration with a composite approach with needling and PRP
29. Post-Burn And Keloid Scar Treatment With Adipose Derived Stems Cells (ADSC)
30. Treatment of chronic wounds with fat grafting and adipose-derived stromal-vascular fraction
31. Fat grafting as an Ancillary treatment for burns and other complex wounds and their sequellae
32. Treatment of scleroderma with Fat grafting, PRP and Adipose stem cells
33. Scar modulations and maturation in post-burn scar contractures and skin grafts using autologous fat injections grafts
34. Complex Regional Pain Syndrome and  Steroid Atrophy Scar Retraction treatment with Adipose Grafting
35. Acute Burns management. The current role of regenerative surgery and its challenges
36. Regenerative surgery choices in Burns sequelae management
37. Fat and stromal cells for acute burn treatment
38. Physical therapies to improve fat grafting and regenerative surgery results in wound healing
39. Combined fat, PRP and Laser for skin and soft tissues regeneration. Clinical applications
40. Regenerative surgery and acellular dermal matrix as reconstructive surgical options in plastic surgery. Theoretical and practical basis
41. The role of adipose tissue graft on nerve regeneration from the perspective of the adipose derived stem cell
42. CellularOptim