This contributed volume presents the current state of research on regenerative rehabilitation across a broad range of neuro- and musculoskeletal tissues. At its core, the primary goal of regenerative rehabilitation is to restore function after damage to bones, skeletal muscles, cartilage, ligaments/tendons, or tissues of the central and peripheral nervous systems. The authors describe the physiology of these neuro- and musculoskeletal tissue types and their inherent plasticity. The latter quality is what enables these tissues to adapt to mechanical and/or chemical cues to improve functional capacity. As a result, readers will learn how regenerative rehabilitation exploits that quality, to trigger positive changes in tissue function.

Combining basic, translational, and clinical aspects of the topic, the book offers a valuable resource for both scientists and clinicians in the regenerative rehabilitation field.

Chapter 1. Historical Perspectives of Regenerative Rehabilitation: Recovering and Restoring Functional Capacity

Chapter 2. Considerations for Small Animal Physical Rehabilitation
Chapter 3. Regenerative Rehabilitation for Nonlethal Muscular Dystrophies
Chapter 4. Regenerative Rehabilitation for Duchenne Muscular Dystrophy
Chapter 5. Regenerative Rehabilitation in Sarcopenia, Dynapenia and Frailty
Chapter 6. Pathophysiology of Volumetric Muscle Loss and Targets for Regenerative Rehabilitation
Chapter 7. Novel Cell-Based Therapeutics for Diseases of the Heart and Skeletal Muscle
Chapter 8. Regenerative Rehabilitation Strategies for Complex Bone Injuries
Chapter 9. Biomaterials in Connective Tissue Regeneration and Rehabilitation
Chapter 10. Ultrasound Stimulation of Tendon Healing: Current Strategies and Opportunities for Novel Therapeutic Approaches
Chapter 11. Mechanical Stimulation as Both the Cause and the Cure of Tendon and Ligament Injuries
Chapter 12. Methods to Enhance the Beneficial Effects of Exercise in Individuals with Spinal Cord Injuries
Chapter 13. Emerging Approaches for Regenerative Rehabilitation Following Traumatic Brain Injury.