Understanding Organic Synthesis

A Systematic Approach to Reaction Classification

Understanding Organic Synthesis

A Systematic Approach to Reaction Classification

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Aimed at graduate students and researchers, this unique text provides a reliable and practical guide to understanding and mastering complex synthesis pathways, explaining essential reaction principles and reagent classifications.

Preface
 
1. Introduction
 
PART I: NUCLEOPHILIC REACTIONS
 
2. Reactions of Alkylating Compounds (A) with Nucleophilic Agents (1-5)
2.1 Inorganic Anions
2.2 Uncharged Nucleophilic Agents
2.3 Organic Anions with a Charge on a Heteroatom
2.4 Carbanions
2.5 Organometallic Compounds
Further Reading
 
3. Reactions of Electrophilic Compounds Containing a Double Bond Between Atoms of Different Electronegativity (B) with Nucleophilic Agents (1-5)
3.1 Inorganic Anions
3.2 Uncharged Nucleophilic Agents
3.3 Organic Anions with a Charge on a Heteroatom
3.4 Carbanions
3.5 Organometallic Compounds
Further Reading
 
4. Reactions of Electrophilic Alkenes (C) with Nucleophilic Agents (1-5)
4.1 Inorganic Anions
4.2 Uncharged Nucleophilic Agents
4.3 Organic Anions with a Charge on a Heteroatom
4.4 Carbanions
4.5 Organometallic Compounds
Further Reading
 
5. Reactions of Aromatic Compounds (D) with Nucleophilic Agents (1-5)
Further Reading
 
6. Reactions of Compounds with an Electrophilic Center on a Heteroatom
(E) with Nucleophilic Agents (1-5)
6.1 Inorganic Anions
6.2 Uncharged Nucleophilic Agents
6.3 Organic Anions with a Charge on a Heteroatom
6.4 Carbanions
6.5 Organometallic Compounds
Further Reading
 
PART II: ELECTROPHILIC REACTIONS
 
7. Interactions of Nucleophilic Compounds (A-C) with Inorganic Cations (1)
 
8. Interactions of Nucleophilic Compounds (A-C) with Uncharged Electrophilic Agents (2)
 
9. Reactions of Nucleophilic Compounds (A-C) with Carbocations (3)
9.1 Inorganic Anions
9.2 p-electron Donors
9.3 pi-electron Donors
Further Reading
 
10. Reactions of Aromatic Compounds (D) with Electrophilic Agents (1-3)
10.1 Inorganic Electrophilic Agents
10.2 Uncharged Electrophilic Agents
10.3 Carbocations
 
11. Reactions of Nucleophilic Compounds (A-D) with Organic Cations with a Charge on a Heteroatom (4)
11.1 Inorganic Anions
11.2 p-electron Donors
11.3 pi-electron Donors
11.4 Aromatic Compounds
Further Reading
 
12. Reactions of Nucleophilic Compounds (A-D) with Electrophilic Carbenes (5)
12.1 Inorganic and Organic Anions
12.2 p-electron Donors
12.3 pi-electron Donors
12.4 Aromatic Compounds
Further Reading
 
13. Rearrangements of Electron-deficient Nitrogen Compounds
Further Reading
 
14. Reactions of Alkenes with Uncharged Electrophilic Agents
14.1 Reactions of Organic Peracids with Alkenes
14.2 Hydroboration Reactions
Further Reading
 
PART III: REACTIONS INVOLVING RADICALS
 
15. Methods of Radicals Generation
Further Reading
 
16. Substitution Reactions
Further Reading
 
17. Radical Addition to Unsaturated Bonds
Further Reading
 
PART IV: PERICYCLIC REACTIONS
 
18. Diels-Alder Reaction
Further Reading
 
19. 1,3-dipolar Cycloaddition Reactions
Further Reading
 
20. [2+2] Cycloaddition Reactions
Further Reading
 
21. Ene Reactions
Further Reading
 
22. Sigmatropic Rearrangements
22.1 Cope Rearrangement
Further Reading
 
Index
 

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ISBN 9783527356676
Medientyp Buch
Auflage 1. Auflage
Copyrightjahr 2026
Verlag Wiley-VCH
Sprache Englisch