Essential Aspects of Immunometabolism in Health and Disease
Immunometabolism has emerged as an intersectional crossroad between metabolism and immune response. Over the past decade, it has become clear that most - if not all - immune cell functions are not separated from cellular metabolism. Although seminal works have addressed the metabolic fate of immune cells during differentiation and function, the physiological status of a given tissue is also dependent on the cell metabolism. The dialogue between immune cells and their microenvironment can also modulate cellular metabolism, which can trigger the onset and progression of a multitude of inflammation-mediated diseases. Thus, uncovering the specific characteristics of the metabolism in different immune cells types and in different conditions, can shed light into the molecular mechanisms of disease and help develop new drugs and therapeutic strategies to treat immune diseases.
The edited volume Essentials aspects of Immunometabolism will give the readers a broad view on howmetabolic pathways can influence many types of immune cells during activation, differentiation and function, in health and disease. Of note, the structure of the book was created thinking not only on the experienced immunologist but also on undergraduate and graduate students, physicians, and all members of the scientific community interested in this exciting field of research.Overview of Immune response
Metabolic Pathway: from biochemistry to bench
Mitochondrial biogenesis and dynamics in healthy and diseases
Epigenetic regulation of metabolic pathways
Metabolic pathways and cells signaling
Metabolic profile of innate and adaptive immune cells
Metabolic sensors and immunopathology
Obesity, metabolic syndrome and inflammation.
Camara, Niels Olsen Saraiva
Alves-Filho, Jose C
Moraes-Vieira, Pedro Manoel Mendes de
Andrade-Oliveira, Vinicius
| ISBN | 978-3-030-86683-9 |
|---|---|
| Artikelnummer | 9783030866839 |
| Medientyp | Buch |
| Copyrightjahr | 2021 |
| Verlag | Springer, Berlin |
| Umfang | XII, 278 Seiten |
| Abbildungen | XII, 278 p. 38 illus., 37 illus. in color. |
| Sprache | Englisch |
