This book contains a series of contributions from internationally renowned academics with special expertise in one or other diseases which collectively are grouped under the heading myeloproliferative disorders. For the editors this term includes Ph-positive chronic myeloid leukemia but also the various Ph-negative variants, some of which provide fascinating insights into the molecular mechanisms of leukemia. There have been many recent developments in understanding the Pathophysiology and a number of therapeutic innovations in this area. One particular merit of this book is the speed with which it has been produced - an important factor in this very rapidly moving field.
1;Preface;5 2;Table of Contents;7 3;Contributors;8 4;Chronic Myeloid Leukemia - A Brief History;11 5;Bcr-Abl and Signal Transduction;24 6;Chronic Myeloid Leukemia: Biology of Advanced Phase;45 7;Clinical Features of CML;67 8;Signal Transduction Inhibitors in Chronic Myeloid Leukemia;83 9;Treatment with Tyrosine Kinase Inhibitors;111 10;Allogeneic Transplantation for CML;122 11;Autografting in Chronic Myeloid Leukemia;139 12;Monitoring Disease Response;148 13;New Therapies for Chronic Myeloid Leukemia;170 14;Immune Therapy of Chronic Myelogenous Leukemia;190 15;Therapeutic Strategies and Concepts of Cure in CML;206 16;BCR-ABL-Negative Chronic Myeloid Leukemia;224 17;Hypereosinophilic Syndrome;239 18;Chronic Idiopathic Myelofibrosis;256 19;Polycythemia Vera - Clinical Aspects;280 20;Polycythemia Vera and Other Polycythemic Disorders - Biological Aspects;300 21;Essential Thrombocythemia;323 22;Subject Index;351
| ISBN | 9783540345060 |
|---|---|
| Artikelnummer | 9783540345060 |
| Medientyp | E-Book - PDF |
| Copyrightjahr | 2007 |
| Verlag | Springer-Verlag |
| Umfang | 354 Seiten |
| Kopierschutz | Digitales Wasserzeichen |
