Technetium-99m Pharmaceuticals
Preparation and Quality Control in Nuclear Medicine
This textbook gives an account of the accomplishments related to the development of 99mTc-radiopharmaceuticals and their application in diagnostic nuclear medicine. Since radioactive drug development is a multi-disciplinary task, experts working in nuclear medicine and research institutions have contributed valuable information concerning the preparation with sterile kits, methods of quality control, and the use of 99mTc-radiopharmaceuticals in patients. In addition, the legal aspects governing production and clinical application are also considered. Section 1 contains basic principles and methods used for analysis. Special emphasis is given to the analytical methods verifying pharmaceutical quality. Section 2 contains monographs of 99mTc-radiopharmaceuticals used in nuclear medicine. Each monograph includes information on the chemistry, formulation, commercial products and trade names, factors affection in-vivo performance, clinical information on pharmacokinetics, as well as details concerning the clinical application and the radiation dose to patients. This book can serve for daily practice in nuclear medicine, serving as a reference source as well as a teaching tool.
1;Foreword;5 2;Preface;8 3;Acknowledgements;9 4;Contents;10 5;List of Contributors;16 6;1 Drug Safety;19 7;2 Technetium in Medicine;22 8;3 Stsannous Chloride in he Preparation of 99m Tc Pharmaceuticals;74 9;4 Quality Assurance of Radiopharmaceuticals;82 10;5 Performance and Quality Control of 99MO/99m TC Generator;91 11;6 Preparation of Technetium 99m TC Pharmaceuticals;108 12;7 Lyophililization Technique ;112 13;8 Cellular Labelling with 99m TC Chelates;116 14;9 Quality Control Methods;136 15;10 Other Technetium Isotopes;164 16;11 The Rules Governing Medicinal Products;167 17;12 Monographs of 99m Tc Pharmaceuticals;183 18;Appendices;348
Zolle, Ilse
| ISBN | 9783540339908 |
|---|---|
| Artikelnummer | 9783540339908 |
| Medientyp | E-Book - PDF |
| Auflage | 2. Aufl. |
| Copyrightjahr | 2007 |
| Verlag | Springer-Verlag |
| Umfang | 345 Seiten |
| Kopierschutz | Digitales Wasserzeichen |
