Leading international experts contribute to this selection of reviews covering the merging fields of growth factors, differentiation factors, and cytokines. These appear to play fundamental roles in a wide variety of physiological and pathophysiological processes that include the regulation of growth in normal and malignant cells, embryogenesis, the immune response, wound healing, inflammation, and atherogenesis. The major aspects of recent research and development are discussed, providing an important update in this pioneering field.

Peptide Growth Factors

Growth Factor Receptors: The Epidermal Growth Factor Receptor as a Model
Epidermal Growth Factor: Biology and Properties of its Gene and Protein Precursor
Platelet-Derived Growth Factor: Formation and Biological Activities
Basic Fibroblast Growth Factor: Properties and Clinical Implications
Transforming Growth Factor-?
Distinctive Features of Nerve Growth Factor: Structure, and Function
Hematopoetic Growth and Differentiation Factors
Interleukin 1
Interleukin 2
Interleukin 3: A Multilineage Hematopoietic Growth Factor
Multiple Functions of Interleukin 4 and its Role in Immune Regulation
Interleukin 5 as a Hematopoietic Cell Growth and Differentiation Factor
Interleukin 6
The Hemopoietic Growth Factor, Granulocyte-Macrophage Colony Stimulating Factor
Colony Stimulating Factor-1
Granulocyte Colony-Stimulating Factor
Chicken Myelomonocytic Growth Factor
Experimental and Clinical Evaluation of Erythropoietin
Interferons
Interactions of 1?,25-Dihydroxyvitamin D3 and Hematopoietic Cells
Oncogenes, Growth Factors, and Disease
Autocrine Stimulation of Growth of Normal and Transformed Cells
Growth Factors, Inflammation, and Atherosclerosis
Autocrine and Paracrine Stimulation of Growth in Human Acute Myeloid Leukemia
Local Production of Platelet-Derived Growth Factor in the Human Atherosclerotic Plaque
Growth Factor Inducible Genes in Fibroblasts
The Role of Gene Dosage in Progression of Tumors
The Biology of Cachectin/Tumor Necrosis Factor
Oncogenes and Transgenic Mice
Mechanisms of Signal Transduction
Growth Factors and Polyphosphoinositide Metabolism
Structure and Function of Signal-Transducing, Heterotrimeric Guanosine Triphosphate Binding Proteins
The Protein Kinase C Family
SignalTransduction and Ion Channel Activity
NA+/H+ Exchange
Adenylyl Cyclases.