Science of Synthesis: Houben-Weyl Methods of Molecular Transformations is the entirely new edition of the acclaimed reference series Houben-Weyl, the standard synthetic chemistry resource since 1909. This new edition is published in English and will comprise 48 volumes published between the years 2000 and 2008.

Science of Synthesis is a quality reference work developed by a highly esteemed editorial board to provide a comprehensive and critical selection of reliable organic and organometallic synthetic methods. This unique resource is designed to be the first point of reference when searching for a synthesis strategy.

• Contains the expertise of presently 400 leading chemists worldwide
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• Discusses relevant background information and provides detailed experimental procedures

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1;Science of Synthesis - Volume 35: Chlorine, Bromine, and Iodine;11.1;Title page;31.2;Imprint;51.3;Preface;61.4;Volume Editor's Preface;81.5;Overview;101.6;Table of Contents;161.7;Introduction;401.8;35.1 Product Class 1: One Saturated Carbon--Chlorine Bond;541.8.1;35.1.1 Product Subclass 1: Chloroalkanes;541.8.1.1;35.1.1.1 Synthesis by Substitution of Hydrogen;581.8.1.1.1;35.1.1.1.1 Alkanes and Cycloalkanes;601.8.1.1.1.1;35.1.1.1.1.1 Method 1: Reactions with Molecular Chlorine;601.8.1.1.1.2;35.1.1.1.1.2 Method 2: Reactions with Sulfuryl Chloride;621.8.1.1.1.3;35.1.1.1.1.3 Method 3: Reactions with Trichloromethanesulfonyl Chloride;631.8.1.1.1.4;35.1.1.1.1.4 Method 4: Reactions with Trichloromethanesulfenyl Chloride;641.8.1.1.1.5;35.1.1.1.1.5 Method 5: Chlorination Reagents Containing an O--Cl Bond;651.8.1.1.1.5.1;35.1.1.1.1.5.1 Variation 1: tert-Butyl Hypochlorite as Chlorine-Atom Donor;651.8.1.1.1.5.2;35.1.1.1.1.5.2 Variation 2: Chlorination with Chlorine Monoxide;651.8.1.1.1.6;35.1.1.1.1.6 Method 6: Reactions with Chloroamines;661.8.1.1.1.7;35.1.1.1.1.7 Method 7: Chlorination with Phosphorus Pentachloride;671.8.1.1.1.8;35.1.1.1.1.8 Method 8: Chlorination Reagents Containing an I--Cl Bond;671.8.1.1.1.8.1;35.1.1.1.1.8.1 Variation 1: (Dichloroiodo)benzene as Chlorine-Atom Donor;671.8.1.1.1.8.2;35.1.1.1.1.8.2 Variation 2: Iodine Trichloride as Chlorine-Atom Donor;681.8.1.1.1.9;35.1.1.1.1.9 Method 9: Chlorination with Carbon Tetrachloride in the Presence of Transition-Metal Carbonyl Complexes;681.8.1.1.2;35.1.1.1.2 Haloalkanes and Halocycloalkanes;691.8.1.1.2.1;35.1.1.1.2.1 Method 1: Reactions with Molecular Chlorine;691.8.1.1.3;35.1.1.1.3 Alcohols;701.8.1.1.3.1;35.1.1.1.3.1 Method 1: Reactions with Molecular Chlorine;701.8.1.1.3.2;35.1.1.1.3.2 Method 2: Reactions with Chloroamines;711.8.1.1.4;35.1.1.1.4 Ethers;711.8.1.1.4.1;35.1.1.1.4.1 Method 1: Reactions with Molecular Chlorine;711.8.1.1.4.2;35.1.1.1.4.2 Method 2: Reactions with Hypohalites;731.8.1.1.4.3;35.1.1.1.4.3 Method 3: Chlorination with (Dichloroiodo)arenes;741.8.1.1.4.4;35.1.1.1.4.4 Method 4: Reactions with Phosphorus Pentachloride;751.8.1.1.5;35.1.1.1.5 Aldehydes;751.8.1.1.5.1;35.1.1.1.5.1 Method 1: Reactions with Sulfuryl Chloride;751.8.1.1.5.2;35.1.1.1.5.2 Method 2: Reactions with N-Chlorosuccinimide;761.8.1.1.6;35.1.1.1.6 Ketones;761.8.1.1.6.1;35.1.1.1.6.1 Method 1: Reactions with Molecular Chlorine;761.8.1.1.6.2;35.1.1.1.6.2 Method 2: Reactions with Manganese(III) Acetate and Lithium Chloride;771.8.1.1.6.3;35.1.1.1.6.3 Method 3: Chlorination with Sulfuryl Chloride;781.8.1.1.7;35.1.1.1.7 Carboxylic Acids and Derivatives;781.8.1.1.7.1;35.1.1.1.7.1 Method 1: Reactions with Molecular Chlorine;781.8.1.1.7.2;35.1.1.1.7.2 Method 2: Reactions with Sulfuryl Chloride;801.8.1.1.7.3;35.1.1.1.7.3 Method 3: Reactions with Chloroamines;811.8.1.1.8;35.1.1.1.8 Amines;821.8.1.1.8.1;35.1.1.1.8.1 Method 1: Reactions with Molecular Chlorine;821.8.1.2;35.1.1.2 Synthesis by Substitution of Metals;861.8.1.2.1;35.1.1.2.1 Method 1: Synthesis from Organo-Group 15 Derivatives;861.8.1.2.2;35.1.1.2.2 Method 2: Synthesis from Trialkylboranes;861.8.1.3;35.1.1.3 Synthesis by Substitution of Carbon Functionalities;881.8.1.3.1;35.1.1.3.1 Method 1: Decarbonylation of Acyl Chlorides;881.8.1.3.2;35.1.1.3.2 Method 2: Chlorodecarboxylation of the Heavy Metal Salts of Carboxylic Acids;881.8.1.3.3;35.1.1.3.3 Method 3: Chlorodecarboxylation of Carboxylic Acids by Lead(IV) Acetate;891.8.1.3.3.1;35.1.1.3.3.1 Variation 1: Chlorodecarboxylation in the Presence of Lithium Chloride;901.8.1.3.3.2;35.1.1.3.3.2 Variation 2: Chlorodecarboxylation in the Presence of N-Chlorosuccinimide;911.8.1.3.4;35.1.1.3.4 Method 4: Chlorodecarboxylation of 1-(Acyloxy)pyridine-2(1H)-thiones;921.8.1.4;35.1.1.4 Synthesis by Substitution of Other Halogens;981.8.1.4.1;35.1.1.4.1 Method 1: Substitution of Bromine;981.8.1.4.2;