Carbonyl and imino groups are two of the most integral functional groups employed in organic synthesis. Specific topics discussed: reduction, alkylation, alkenylation, and arylation of these groups, as well as asymmetric aldol, Mannich, and Morita-Bayliss-Hillman reactions.

This volume is part of a 3-volume set: Science of Synthesis Stereoselective Synthesis Workbench Edition

Further information about Stereoselective Synthesis (including sample pages and the table of contents)

1;Science of Synthesis: Stereoselective Synthesis 2 - Stereoselective Reactions of Carbonyl and Imino Groups;11.1;Organizational Structure of Science of Synthesis;21.2;Science of Synthesis Reference Library;31.3;Title page;51.4;Imprint;71.5;Preface;81.6;Volume Editors' Preface;101.7;Stereoselective Synthesis Volumes;121.8;Abstracts;141.9;Overview;241.10;Table of Contents;261.11;Introduction;441.12;2.1 Reduction of Carbonyl Groups: Hydrogenation;521.12.1;2.1.1 Diastereoselective Hydrogenation of Carbonyl Groups;541.12.1.1;2.1.1.1 Diastereoselection Based on Steric Hindrance;541.12.1.2;2.1.1.2 Diastereoselection through Chelate Intermediates;571.12.2;2.1.2 Enantioselective Hydrogenation of Carbonyl Groups;591.12.2.1;2.1.2.1 Hydrogenation of Functionalized Ketones;591.12.2.1.1;2.1.2.1.1 Hydrogenation of ß-Keto Esters;591.12.2.1.2;2.1.2.1.2 Hydrogenation of a-Substituted ß-Keto Esters: Dynamic Kinetic Resolution;671.12.2.1.3;2.1.2.1.3 Hydrogenation of a-Keto Esters;691.12.2.1.4;2.1.2.1.4 Hydrogenation of Miscellaneous Substrates;711.12.2.2;2.1.2.2 Hydrogenation of Simple Ketones;731.12.2.2.1;2.1.2.2.1 Hydrogenation of Aromatic Ketones;731.12.2.2.2;2.1.2.2.2 Hydrogenation of Unsaturated Ketones (Alkenyl Alkyl Ketones);891.12.2.2.3;2.1.2.2.3 Hydrogenation of Alkyl Ketones;921.12.2.2.4;2.1.2.2.4 Hydrogenation of Acylsilanes;951.13;2.2 Reduction of Carbonyl Groups: Transfer Hydrogenation, Hydrosilylation, Catalytic Hydroboration, and Reduction with Borohydrides, Aluminum Hydrides, or Boranes;1021.13.1;2.2.1 Transfer Hydrogenation;1021.13.1.1;2.2.1.1 The Meerwein--Ponndorf--Verley Reduction of Ketones;1031.13.1.1.1;2.2.1.1.1 Diastereoselective Reduction;1031.13.1.1.2;2.2.1.1.2 Enantioselective Reduction;1081.13.1.2;2.2.1.2 Asymmetric Transfer Hydrogenation of Ketones Catalyzed by Group 8 and 9 Metal Complexes;1081.13.1.2.1;2.2.1.2.1 Reduction in Organic Solvents;1081.13.1.2.2;2.2.1.2.2 Reduction in Water;1211.13.1.2.3;2.2.1.2.3 Immobilized Catalysts;1241.13.1.2.4;2.2.1.2.4 Biomimetic Reduction;1251.13.2;2.2.2 Hydrosilylation of Ketones;1271.13.2.1;2.2.2.1 Hydrosilylation Catalyzed by Rhodium Complexes;1281.13.2.2;2.2.2.2 Titanium Hydride Catalyzed Hydrosilylation;1321.13.2.3;2.2.2.3 Copper Hydride Catalyzed Hydrosilylation;1331.13.2.4;2.2.2.4 Organocatalytic Hydrosilylation;1361.13.2.4.1;2.2.2.4.1 Diastereoselective Reduction;1361.13.2.4.2;2.2.2.4.2 Enantioselective Reduction;1381.13.3;2.2.3 Asymmetric Catalytic Hydroboration;1391.13.3.1;2.2.3.1 Hydroboration of Ketones Catalyzed by Oxazaborolidines;1391.13.3.2;2.2.3.2 Hydroboration of Functionalized Ketones Catalyzed by Oxazaborolidines;1451.13.3.3;2.2.3.3 Hydroboration of Ketones Catalyzed by (Aminoalkoxy)boranes and Aminoborates;1491.13.4;2.2.4 Reduction with Borohydrides, Aluminum Hydrides, and Boranes;1531.13.4.1;2.2.4.1 Diastereoselective Reduction of Ketones;1531.13.4.2;2.2.4.2 Enantioselective Reduction of Aldehydes and Ketones;1571.14;2.3 Enzymatic Reduction of Carbonyl Groups;1761.14.1;2.3.1 Alcohol Dehydrogenases (Ketoreductases): The Enzymes for Carbonyl Reduction;1771.14.1.1;2.3.1.1 Reduction of Ketones Mediated by Wild-Type Whole Cells, Engineered Whole Cells, Enzyme Preparations, and Immobilized Enzymes;1781.14.1.1.1;2.3.1.1.1 Whole-Cell Reductions with Wild-Type Organisms;1791.14.1.1.2;2.3.1.1.2 Enzymes from Genetically Engineered Organisms;1831.14.1.1.3;2.3.1.1.3 Comparison of Enzyme Formulations;1841.14.1.1.4;2.3.1.1.4 General Aspects of Working with Whole Cells and Enzyme Preparations;1851.14.1.2;2.3.1.2 Availability of Alcohol Dehydrogenases;1861.14.1.3;2.3.1.3 Selection of an Alcohol Dehydrogenase;1861.14.2;2.3.2 Selection of Reaction Conditions;1871.14.2.1;2.3.2.1 Cofactor Regeneration Systems;1871.14.2.1.1;2.3.2.1.1 Cofactor Regeneration by Glucose Dehydrogenase;1871.14.2.1.2;2.3.2.1.2 Cofactor Regeneration by Formate Dehydrogenase;1891.14.2.1.3;2.3