This book provides a comprehensive and up-to-date review of the basic and clinical aspects of infections and infectious processes that trigger or aggravate a variety of autoimmune and inflammatory musculoskeletal disorders. It delivers a timely update on the interactions between infection and rheumatic diseases in order to provide clinicians with the tools they need for proper diagnosis and treatment.

The book is divided into five main sections. The first examines the basic aspects of bacterial infections with a discussion of molecular biology, the microbiome, various types of bacteria that cause infection, and recent advances in biologic therapy. The next section focuses on different forms of viral arthritis including hepatitis arthritis, arthritis associated with alpha viruses, and parvovirus-related arthritis. Subsequent chapters then discuss arthritis caused by mycobacteria, fungi, spirochete, and other miscellaneous arthritides. Following this are various analyzations onreactive arthritis and infection-related rheumatic diseases such as Whipple's Disease, SAPHO Syndrome, rheumatic fever, and HIV-associated rheumatic manifestations. Finally, the book closes with three chapters on external impacts on infectious diseases such as climate change, vaccinations and systemic lupus erythematosus.

Infections and the Rheumatic Diseases is an essential resource for physicians and related professionals, residents, fellows, graduate students, and nurses in rheumatology, clinical immunology, and internal medicine.

Part I. Basic Aspects of Bacterial Infections.- Chapter 1. The Molecular Biology of Chlamydiae as Exemplar of Bacterial Pathogenesis in the Rheumatic Diseases..- Chapter 2. Microbiome and Microbiota in Rheumatic Disease.- Chapter 3. Gonococcal and Nongonococcal Bacterial Infections.- Chapter 4. Septic Arthritis in Children: Clinical Update

5. Salmonella Arthritis.- Chapter 6. BrucellarArthritis.- Chapter 7. Prosthetic Septic Arthritis: Etiology, Clinical Aspects, and Management.- Chapter 8. Opportunistic Infections Associated with Biologic Therapy.- Part II. Viral Arthritides.- Chapter 9. The Pathophysiology of Arthritis Due to Viruses and Vaccines.- Chapter 10. Hepatitis Arthritis: HBV and HCV.- Chapter 11. Arthritis Associated with Alphavirus Infections: Chikungunya
12. Arthritis Associated with Alphavirus Infections: Dengue and Zika.- Chapter 13. Ebola Virus Disease Musculoskeletal Manifestations
14. Parvovirus-Related Arthritis.- Chapter 15. Human Immunodeficiency Virus Infection:Spectrum of Rheumatic Manifestations
16. HTLV-1: A View from the Rheumatologist
17. Other Viral Arthritides.- Part III. Arthritis Due to Mycobacteria, Fungi, Spirochete, and Miscellaneous Arthritides.- Chapter 18. Tuberculous and Nontuberculous Mycobacterial Infections
19. Leprosy-Associated Arthritis
20. Coccidioidal Arthritis
21. Histoplasmosis: Musculoskeletal Manifestations
22. Blastomycosis Arthritis.- Chapter 23. Candida Arthritis.- Chapter 24. Other Fungal Arthritis.- Chapter 25. Syphilis-Related Musculoskeletal Manifestations.- Chapter 26. Lyme Disease and Arthritis.- Chapter 27. Mycoplasmal Arthritis.- Chapter 28. Parasitic Arthritis
Chapter 29. Whipple Disease.-  Part IV: Arthritis Due to Other Bacteria, Mycobacteria, Fungi, Spirochete, and Parasites.- Chapter 30. Infection and Spondyloarthritis
Chapter 31. Acute Rheumatic Fever
Chapter 32. Pathophysiology of Reactive Arthritis
Chapter 33. The Major Histocompatibility Complex and Reactive Arthritis
Chapter 34. Reactive Arthritis: Animal Models
Chapter 35. Reactive Arthritis: Clinical Features and Treatment
Chapter 36. Psoriatic Arthritis and Infection
Chapter 37. Microbes in the Pathogenesis of Inflammatory Bowel Disease: A Review.- Part V Miscellaneous.- Chapter 38. Infections in Systemic Lupus Erythematosus
Chapter 39. Vaccines in Rheumatic Diseases
Chapter 40. Climate Change: Impact on Infectious Diseases.